Preparation of Cationic Amphiphilic Nanoparticles with Modified Chitosan Derivatives for Doxorubicin Delivery

Polymeric micelle-like nanoparticles have demonstrated effectiveness for the delivery of some poorly soluble or hydrophobic anticancer drugs. In this study, a hydrophobic moiety, deoxycholic acid (DCA) was first bonded on a polysaccharide, chitosan (CS), for the preparation of amphiphilic chitosan (...

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Bibliographic Details
Main Authors: Xiudong Liu, Huofei Zhou, Weiting Yu, Xin Xiong, Rumen Krastev, Xiaojun Ma
Format: article
Language:EN
Published: MDPI AG 2021
Subjects:
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Online Access:https://doaj.org/article/d7dc7d719a53461d936425a5b8d3c25b
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