A systematic review and meta-analysis of the prevalence and determinants of gestational diabetes mellitus in Nigeria

Background: Gestational diabetes mellitus (GDM) is any degree of glucose intolerance with onset or first diagnosis in pregnancy. GDM has numerous potential complications and it is important to estimate its burden and risk factors. The objective of the meta-analysis was to determine the pooled preval...

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Autores principales:	Taoreed Adegoke Azeez, Tamunosaki Abo-Briggs, Ayodeji Sylvester Adeyanju
Formato:	article
Lenguaje:	EN
Publicado:	Wolters Kluwer Medknow Publications 2021
Materias:	gestational diabetes meta-analysis nigeria prevalence risk factors Diseases of the endocrine glands. Clinical endocrinology RC648-665 Diseases of the digestive system. Gastroenterology RC799-869
Acceso en línea:	https://doaj.org/article/d7dff48d8b784a418fb56488e98e534d
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spelling	oai:doaj.org-article:d7dff48d8b784a418fb56488e98e534d2021-11-12T10:10:55ZA systematic review and meta-analysis of the prevalence and determinants of gestational diabetes mellitus in Nigeria2230-821010.4103/ijem.ijem_301_21https://doaj.org/article/d7dff48d8b784a418fb56488e98e534d2021-01-01T00:00:00Zhttp://www.ijem.in/article.asp?issn=2230-8210;year=2021;volume=25;issue=3;spage=182;epage=190;aulast=Azeezhttps://doaj.org/toc/2230-8210Background: Gestational diabetes mellitus (GDM) is any degree of glucose intolerance with onset or first diagnosis in pregnancy. GDM has numerous potential complications and it is important to estimate its burden and risk factors. The objective of the meta-analysis was to determine the pooled prevalence of GDM in Nigeria and identify its determinants. Methods: The study design was a meta-analysis; therefore the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines were followed. Electronic databases (African Journal Online, PubMed, SCOPUS, and Google Scholar) and the gray literature were systematically searched. Statistical analysis was done with MetaXL using the random effect model. Heterogeneity was determined using the I2 statistic and the publication bias was checked with the Doi plot. Results: The total sample size was 46 210. The prevalence of GDM in Nigeria was 0.5 – 38% and the pooled prevalence was 11.0% (95% CI 8-13). The I2 statistic was 99%. The Doi plot suggested some degree of bias. The most frequently reported determinants of GDM were previous macrosomic babies, maternal obesity, family history of diabetes, previous miscarriage, and advanced maternal age. Conclusion: The prevalence of GDM in Nigeria is high and efforts should be geared at modifying its risk factors so as to reduce its prevalence and prevent the associated complications.Taoreed Adegoke AzeezTamunosaki Abo-BriggsAyodeji Sylvester AdeyanjuWolters Kluwer Medknow Publicationsarticlegestational diabetesmeta-analysisnigeriaprevalencerisk factorsDiseases of the endocrine glands. Clinical endocrinologyRC648-665Diseases of the digestive system. GastroenterologyRC799-869ENIndian Journal of Endocrinology and Metabolism, Vol 25, Iss 3, Pp 182-190 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	gestational diabetes meta-analysis nigeria prevalence risk factors Diseases of the endocrine glands. Clinical endocrinology RC648-665 Diseases of the digestive system. Gastroenterology RC799-869
spellingShingle	gestational diabetes meta-analysis nigeria prevalence risk factors Diseases of the endocrine glands. Clinical endocrinology RC648-665 Diseases of the digestive system. Gastroenterology RC799-869 Taoreed Adegoke Azeez Tamunosaki Abo-Briggs Ayodeji Sylvester Adeyanju A systematic review and meta-analysis of the prevalence and determinants of gestational diabetes mellitus in Nigeria
description	Background: Gestational diabetes mellitus (GDM) is any degree of glucose intolerance with onset or first diagnosis in pregnancy. GDM has numerous potential complications and it is important to estimate its burden and risk factors. The objective of the meta-analysis was to determine the pooled prevalence of GDM in Nigeria and identify its determinants. Methods: The study design was a meta-analysis; therefore the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines were followed. Electronic databases (African Journal Online, PubMed, SCOPUS, and Google Scholar) and the gray literature were systematically searched. Statistical analysis was done with MetaXL using the random effect model. Heterogeneity was determined using the I2 statistic and the publication bias was checked with the Doi plot. Results: The total sample size was 46 210. The prevalence of GDM in Nigeria was 0.5 – 38% and the pooled prevalence was 11.0% (95% CI 8-13). The I2 statistic was 99%. The Doi plot suggested some degree of bias. The most frequently reported determinants of GDM were previous macrosomic babies, maternal obesity, family history of diabetes, previous miscarriage, and advanced maternal age. Conclusion: The prevalence of GDM in Nigeria is high and efforts should be geared at modifying its risk factors so as to reduce its prevalence and prevent the associated complications.
format	article
author	Taoreed Adegoke Azeez Tamunosaki Abo-Briggs Ayodeji Sylvester Adeyanju
author_facet	Taoreed Adegoke Azeez Tamunosaki Abo-Briggs Ayodeji Sylvester Adeyanju
author_sort	Taoreed Adegoke Azeez
title	A systematic review and meta-analysis of the prevalence and determinants of gestational diabetes mellitus in Nigeria
title_short	A systematic review and meta-analysis of the prevalence and determinants of gestational diabetes mellitus in Nigeria
title_full	A systematic review and meta-analysis of the prevalence and determinants of gestational diabetes mellitus in Nigeria
title_fullStr	A systematic review and meta-analysis of the prevalence and determinants of gestational diabetes mellitus in Nigeria
title_full_unstemmed	A systematic review and meta-analysis of the prevalence and determinants of gestational diabetes mellitus in Nigeria
title_sort	systematic review and meta-analysis of the prevalence and determinants of gestational diabetes mellitus in nigeria
publisher	Wolters Kluwer Medknow Publications
publishDate	2021
url	https://doaj.org/article/d7dff48d8b784a418fb56488e98e534d
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A systematic review and meta-analysis of the prevalence and determinants of gestational diabetes mellitus in Nigeria

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