The Prolactin Family of Hormones as Regulators of Maternal Mood and Behavior

Transition into motherhood involves profound physiological and behavioral adaptations that ensure the healthy development of offspring while maintaining maternal health. Dynamic fluctuations in key hormones during pregnancy and lactation induce these maternal adaptations by acting on neural circuits...

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Autores principales:	Teodora Georgescu, Judith M. Swart, David R. Grattan, Rosemary S. E. Brown
Formato:	article
Lenguaje:	EN
Publicado:	Frontiers Media S.A. 2021
Materias:	prolactin placental lactogen (PL) prolactin receptor maternal behavior maternal mood neuroendocrinology Gynecology and obstetrics RG1-991 Women. Feminism HQ1101-2030.7
Acceso en línea:	https://doaj.org/article/d7eb26ed4653465a81da9652135a7867
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spelling	oai:doaj.org-article:d7eb26ed4653465a81da9652135a78672021-12-01T22:37:21ZThe Prolactin Family of Hormones as Regulators of Maternal Mood and Behavior2673-505910.3389/fgwh.2021.767467https://doaj.org/article/d7eb26ed4653465a81da9652135a78672021-12-01T00:00:00Zhttps://www.frontiersin.org/articles/10.3389/fgwh.2021.767467/fullhttps://doaj.org/toc/2673-5059Transition into motherhood involves profound physiological and behavioral adaptations that ensure the healthy development of offspring while maintaining maternal health. Dynamic fluctuations in key hormones during pregnancy and lactation induce these maternal adaptations by acting on neural circuits in the brain. Amongst these hormonal changes, lactogenic hormones (e.g., prolactin and its pregnancy-specific homolog, placental lactogen) are important regulators of these processes, and their receptors are located in key brain regions controlling emotional behaviors and maternal responses. With pregnancy and lactation also being associated with a marked elevation in the risk of developing mood disorders, it is important to understand how hormones are normally regulating mood and behavior during this time. It seems likely that pathological changes in mood could result from aberrant expression of these hormone-induced behavioral responses. Maternal mental health problems during pregnancy and the postpartum period represent a major barrier in developing healthy mother-infant interactions which are crucial for the child's development. In this review, we will examine the role lactogenic hormones play in driving a range of specific maternal behaviors, including motivation, protectiveness, and mother-pup interactions. Understanding how these hormones collectively act in a mother's brain to promote nurturing behaviors toward offspring will ultimately assist in treatment development and contribute to safeguarding a successful pregnancy.Teodora GeorgescuTeodora GeorgescuTeodora GeorgescuJudith M. SwartJudith M. SwartJudith M. SwartDavid R. GrattanDavid R. GrattanDavid R. GrattanRosemary S. E. BrownRosemary S. E. BrownFrontiers Media S.A.articleprolactinplacental lactogen (PL)prolactin receptormaternal behaviormaternal moodneuroendocrinologyGynecology and obstetricsRG1-991Women. FeminismHQ1101-2030.7ENFrontiers in Global Women's Health, Vol 2 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	prolactin placental lactogen (PL) prolactin receptor maternal behavior maternal mood neuroendocrinology Gynecology and obstetrics RG1-991 Women. Feminism HQ1101-2030.7
spellingShingle	prolactin placental lactogen (PL) prolactin receptor maternal behavior maternal mood neuroendocrinology Gynecology and obstetrics RG1-991 Women. Feminism HQ1101-2030.7 Teodora Georgescu Teodora Georgescu Teodora Georgescu Judith M. Swart Judith M. Swart Judith M. Swart David R. Grattan David R. Grattan David R. Grattan Rosemary S. E. Brown Rosemary S. E. Brown The Prolactin Family of Hormones as Regulators of Maternal Mood and Behavior
description	Transition into motherhood involves profound physiological and behavioral adaptations that ensure the healthy development of offspring while maintaining maternal health. Dynamic fluctuations in key hormones during pregnancy and lactation induce these maternal adaptations by acting on neural circuits in the brain. Amongst these hormonal changes, lactogenic hormones (e.g., prolactin and its pregnancy-specific homolog, placental lactogen) are important regulators of these processes, and their receptors are located in key brain regions controlling emotional behaviors and maternal responses. With pregnancy and lactation also being associated with a marked elevation in the risk of developing mood disorders, it is important to understand how hormones are normally regulating mood and behavior during this time. It seems likely that pathological changes in mood could result from aberrant expression of these hormone-induced behavioral responses. Maternal mental health problems during pregnancy and the postpartum period represent a major barrier in developing healthy mother-infant interactions which are crucial for the child's development. In this review, we will examine the role lactogenic hormones play in driving a range of specific maternal behaviors, including motivation, protectiveness, and mother-pup interactions. Understanding how these hormones collectively act in a mother's brain to promote nurturing behaviors toward offspring will ultimately assist in treatment development and contribute to safeguarding a successful pregnancy.
format	article
author	Teodora Georgescu Teodora Georgescu Teodora Georgescu Judith M. Swart Judith M. Swart Judith M. Swart David R. Grattan David R. Grattan David R. Grattan Rosemary S. E. Brown Rosemary S. E. Brown
author_facet	Teodora Georgescu Teodora Georgescu Teodora Georgescu Judith M. Swart Judith M. Swart Judith M. Swart David R. Grattan David R. Grattan David R. Grattan Rosemary S. E. Brown Rosemary S. E. Brown
author_sort	Teodora Georgescu
title	The Prolactin Family of Hormones as Regulators of Maternal Mood and Behavior
title_short	The Prolactin Family of Hormones as Regulators of Maternal Mood and Behavior
title_full	The Prolactin Family of Hormones as Regulators of Maternal Mood and Behavior
title_fullStr	The Prolactin Family of Hormones as Regulators of Maternal Mood and Behavior
title_full_unstemmed	The Prolactin Family of Hormones as Regulators of Maternal Mood and Behavior
title_sort	prolactin family of hormones as regulators of maternal mood and behavior
publisher	Frontiers Media S.A.
publishDate	2021
url	https://doaj.org/article/d7eb26ed4653465a81da9652135a7867
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The Prolactin Family of Hormones as Regulators of Maternal Mood and Behavior

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