Proteome-wide and matrisome-specific alterations during human pancreas development and maturation

The pancreatic extracellular matrix (ECM) is known to differ between species, age groups and physiological states, but its compositional changes throughout human life are not well understood. Here, the authors study how the proteome of pancreatic ECM changes during human development and maturation.

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Autores principales: Zihui Li, Daniel M. Tremmel, Fengfei Ma, Qinying Yu, Min Ma, Daniel G. Delafield, Yatao Shi, Bin Wang, Samantha A. Mitchell, Austin K. Feeney, Vansh S. Jain, Sara Dutton Sackett, Jon S. Odorico, Lingjun Li
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Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/d7edcdc9528d41d2934319ee28806e54
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spelling oai:doaj.org-article:d7edcdc9528d41d2934319ee28806e542021-12-02T14:21:30ZProteome-wide and matrisome-specific alterations during human pancreas development and maturation10.1038/s41467-021-21261-w2041-1723https://doaj.org/article/d7edcdc9528d41d2934319ee28806e542021-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-21261-whttps://doaj.org/toc/2041-1723The pancreatic extracellular matrix (ECM) is known to differ between species, age groups and physiological states, but its compositional changes throughout human life are not well understood. Here, the authors study how the proteome of pancreatic ECM changes during human development and maturation.Zihui LiDaniel M. TremmelFengfei MaQinying YuMin MaDaniel G. DelafieldYatao ShiBin WangSamantha A. MitchellAustin K. FeeneyVansh S. JainSara Dutton SackettJon S. OdoricoLingjun LiNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Zihui Li
Daniel M. Tremmel
Fengfei Ma
Qinying Yu
Min Ma
Daniel G. Delafield
Yatao Shi
Bin Wang
Samantha A. Mitchell
Austin K. Feeney
Vansh S. Jain
Sara Dutton Sackett
Jon S. Odorico
Lingjun Li
Proteome-wide and matrisome-specific alterations during human pancreas development and maturation
description The pancreatic extracellular matrix (ECM) is known to differ between species, age groups and physiological states, but its compositional changes throughout human life are not well understood. Here, the authors study how the proteome of pancreatic ECM changes during human development and maturation.
format article
author Zihui Li
Daniel M. Tremmel
Fengfei Ma
Qinying Yu
Min Ma
Daniel G. Delafield
Yatao Shi
Bin Wang
Samantha A. Mitchell
Austin K. Feeney
Vansh S. Jain
Sara Dutton Sackett
Jon S. Odorico
Lingjun Li
author_facet Zihui Li
Daniel M. Tremmel
Fengfei Ma
Qinying Yu
Min Ma
Daniel G. Delafield
Yatao Shi
Bin Wang
Samantha A. Mitchell
Austin K. Feeney
Vansh S. Jain
Sara Dutton Sackett
Jon S. Odorico
Lingjun Li
author_sort Zihui Li
title Proteome-wide and matrisome-specific alterations during human pancreas development and maturation
title_short Proteome-wide and matrisome-specific alterations during human pancreas development and maturation
title_full Proteome-wide and matrisome-specific alterations during human pancreas development and maturation
title_fullStr Proteome-wide and matrisome-specific alterations during human pancreas development and maturation
title_full_unstemmed Proteome-wide and matrisome-specific alterations during human pancreas development and maturation
title_sort proteome-wide and matrisome-specific alterations during human pancreas development and maturation
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/d7edcdc9528d41d2934319ee28806e54
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