Human Melioidosis Caused by Novel Transmission of Burkholderia pseudomallei from Freshwater Home Aquarium, United States
Nearly all cases of melioidosis in the continental United States are related to international travel to areas to which Burkholderia pseudomallei, the bacterium that causes melioidosis, is endemic. We report the diagnosis and clinical course of melioidosis in a patient from the United States who had...
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Centers for Disease Control and Prevention
2021
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oai:doaj.org-article:d7eea9b0c7f84661b89bf5565007f7332021-11-22T12:56:51ZHuman Melioidosis Caused by Novel Transmission of Burkholderia pseudomallei from Freshwater Home Aquarium, United States10.3201/eid2712.2117561080-60401080-6059https://doaj.org/article/d7eea9b0c7f84661b89bf5565007f7332021-12-01T00:00:00Zhttps://wwwnc.cdc.gov/eid/article/27/12/21-1756_articlehttps://doaj.org/toc/1080-6040https://doaj.org/toc/1080-6059 Nearly all cases of melioidosis in the continental United States are related to international travel to areas to which Burkholderia pseudomallei, the bacterium that causes melioidosis, is endemic. We report the diagnosis and clinical course of melioidosis in a patient from the United States who had no international travel history and the public health investigation to determine the source of exposure. We tested environmental samples collected from the patient’s home for B. pseudomallei by PCR and culture. Whole-genome sequencing was conducted on PCR-positive environmental samples, and results were compared with sequences from the patient’s clinical specimen. Three PCR-positive environmental samples, all collected from a freshwater home aquarium that had contained imported tropical fish, were a genetic match to the clinical isolate from the patient. This finding suggests a novel route of exposure and a potential for importation of B. pseudomallei, a select agent, into the United States from disease-endemic areas. Patrick DawsonMonique M. DuwellMindy G. ElrodRuth J. ThompsonDavid A. CrumRuth M. JacobsJay E. GeeCari B. KoltonLindy LiuDavid D. BlaneyLaToya Griffin ThomasDenise SockwellZachary WeinerWilliam A. BowerAlex R. HoffmasterJohanna S. SalzerCenters for Disease Control and PreventionarticlemelioidosisBurkholderia pseudomalleibacteriaOne Healthtransmissionfreshwater home aquariumMedicineRInfectious and parasitic diseasesRC109-216ENEmerging Infectious Diseases, Vol 27, Iss 12, Pp 3030-3035 (2021) |
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DOAJ |
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EN |
| topic |
melioidosis Burkholderia pseudomallei bacteria One Health transmission freshwater home aquarium Medicine R Infectious and parasitic diseases RC109-216 |
| spellingShingle |
melioidosis Burkholderia pseudomallei bacteria One Health transmission freshwater home aquarium Medicine R Infectious and parasitic diseases RC109-216 Patrick Dawson Monique M. Duwell Mindy G. Elrod Ruth J. Thompson David A. Crum Ruth M. Jacobs Jay E. Gee Cari B. Kolton Lindy Liu David D. Blaney LaToya Griffin Thomas Denise Sockwell Zachary Weiner William A. Bower Alex R. Hoffmaster Johanna S. Salzer Human Melioidosis Caused by Novel Transmission of Burkholderia pseudomallei from Freshwater Home Aquarium, United States |
| description |
Nearly all cases of melioidosis in the continental United States are related to international travel to areas to which Burkholderia pseudomallei, the bacterium that causes melioidosis, is endemic. We report the diagnosis and clinical course of melioidosis in a patient from the United States who had no international travel history and the public health investigation to determine the source of exposure. We tested environmental samples collected from the patient’s home for B. pseudomallei by PCR and culture. Whole-genome sequencing was conducted on PCR-positive environmental samples, and results were compared with sequences from the patient’s clinical specimen. Three PCR-positive environmental samples, all collected from a freshwater home aquarium that had contained imported tropical fish, were a genetic match to the clinical isolate from the patient. This finding suggests a novel route of exposure and a potential for importation of B. pseudomallei, a select agent, into the United States from disease-endemic areas.
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| format |
article |
| author |
Patrick Dawson Monique M. Duwell Mindy G. Elrod Ruth J. Thompson David A. Crum Ruth M. Jacobs Jay E. Gee Cari B. Kolton Lindy Liu David D. Blaney LaToya Griffin Thomas Denise Sockwell Zachary Weiner William A. Bower Alex R. Hoffmaster Johanna S. Salzer |
| author_facet |
Patrick Dawson Monique M. Duwell Mindy G. Elrod Ruth J. Thompson David A. Crum Ruth M. Jacobs Jay E. Gee Cari B. Kolton Lindy Liu David D. Blaney LaToya Griffin Thomas Denise Sockwell Zachary Weiner William A. Bower Alex R. Hoffmaster Johanna S. Salzer |
| author_sort |
Patrick Dawson |
| title |
Human Melioidosis Caused by Novel Transmission of Burkholderia pseudomallei from Freshwater Home Aquarium, United States |
| title_short |
Human Melioidosis Caused by Novel Transmission of Burkholderia pseudomallei from Freshwater Home Aquarium, United States |
| title_full |
Human Melioidosis Caused by Novel Transmission of Burkholderia pseudomallei from Freshwater Home Aquarium, United States |
| title_fullStr |
Human Melioidosis Caused by Novel Transmission of Burkholderia pseudomallei from Freshwater Home Aquarium, United States |
| title_full_unstemmed |
Human Melioidosis Caused by Novel Transmission of Burkholderia pseudomallei from Freshwater Home Aquarium, United States |
| title_sort |
human melioidosis caused by novel transmission of burkholderia pseudomallei from freshwater home aquarium, united states |
| publisher |
Centers for Disease Control and Prevention |
| publishDate |
2021 |
| url |
https://doaj.org/article/d7eea9b0c7f84661b89bf5565007f733 |
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