Subtomogram averaging of COPII assemblies reveals how coat organization dictates membrane shape

The COPII coat assembles in two concentric layers and mediates protein export from the endoplasmic reticulum. Here the authors present the 4.9 Å resolution cryo-tomography and subtomogram averaging structure of the membrane bound COPII inner coat that was obtained by in vitro reconstitution and disc...

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Main Authors:	Joshua Hutchings, Viktoriya Stancheva, Elizabeth A. Miller, Giulia Zanetti
Format:	article
Language:	EN
Published:	Nature Portfolio 2018
Subjects:	Science Q
Online Access:	https://doaj.org/article/d805b15fd8a0450ebdba300c73ed8311
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id	oai:doaj.org-article:d805b15fd8a0450ebdba300c73ed8311
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spelling	oai:doaj.org-article:d805b15fd8a0450ebdba300c73ed83112021-12-02T14:40:04ZSubtomogram averaging of COPII assemblies reveals how coat organization dictates membrane shape10.1038/s41467-018-06577-42041-1723https://doaj.org/article/d805b15fd8a0450ebdba300c73ed83112018-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06577-4https://doaj.org/toc/2041-1723The COPII coat assembles in two concentric layers and mediates protein export from the endoplasmic reticulum. Here the authors present the 4.9 Å resolution cryo-tomography and subtomogram averaging structure of the membrane bound COPII inner coat that was obtained by in vitro reconstitution and discuss mechanistic implications.Joshua HutchingsViktoriya StanchevaElizabeth A. MillerGiulia ZanettiNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-8 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Joshua Hutchings Viktoriya Stancheva Elizabeth A. Miller Giulia Zanetti Subtomogram averaging of COPII assemblies reveals how coat organization dictates membrane shape
description	The COPII coat assembles in two concentric layers and mediates protein export from the endoplasmic reticulum. Here the authors present the 4.9 Å resolution cryo-tomography and subtomogram averaging structure of the membrane bound COPII inner coat that was obtained by in vitro reconstitution and discuss mechanistic implications.
format	article
author	Joshua Hutchings Viktoriya Stancheva Elizabeth A. Miller Giulia Zanetti
author_facet	Joshua Hutchings Viktoriya Stancheva Elizabeth A. Miller Giulia Zanetti
author_sort	Joshua Hutchings
title	Subtomogram averaging of COPII assemblies reveals how coat organization dictates membrane shape
title_short	Subtomogram averaging of COPII assemblies reveals how coat organization dictates membrane shape
title_full	Subtomogram averaging of COPII assemblies reveals how coat organization dictates membrane shape
title_fullStr	Subtomogram averaging of COPII assemblies reveals how coat organization dictates membrane shape
title_full_unstemmed	Subtomogram averaging of COPII assemblies reveals how coat organization dictates membrane shape
title_sort	subtomogram averaging of copii assemblies reveals how coat organization dictates membrane shape
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/d805b15fd8a0450ebdba300c73ed8311
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_version_	1718390446073315328

Subtomogram averaging of COPII assemblies reveals how coat organization dictates membrane shape

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