Gs-coupled GPCR signalling in AgRP neurons triggers sustained increase in food intake

Hypothalamic Agouti-related peptide (AgRP) neurons play a key role in regulating food intake. Here, the authors report a novel pathway in which activation of Gs-coupled receptors on AgRP neurons leads to robust, sustained increase in food intake.

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Autores principales: Ken-ichiro Nakajima, Zhenzhong Cui, Chia Li, Jaroslawna Meister, Yinghong Cui, Ou Fu, Adam S. Smith, Shalini Jain, Bradford B. Lowell, Michael J. Krashes, Jürgen Wess
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/d80731cbf6a5433fb3c995ee37ce1bac
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spelling oai:doaj.org-article:d80731cbf6a5433fb3c995ee37ce1bac2021-12-02T17:31:49ZGs-coupled GPCR signalling in AgRP neurons triggers sustained increase in food intake10.1038/ncomms102682041-1723https://doaj.org/article/d80731cbf6a5433fb3c995ee37ce1bac2016-01-01T00:00:00Zhttps://doi.org/10.1038/ncomms10268https://doaj.org/toc/2041-1723Hypothalamic Agouti-related peptide (AgRP) neurons play a key role in regulating food intake. Here, the authors report a novel pathway in which activation of Gs-coupled receptors on AgRP neurons leads to robust, sustained increase in food intake.Ken-ichiro NakajimaZhenzhong CuiChia LiJaroslawna MeisterYinghong CuiOu FuAdam S. SmithShalini JainBradford B. LowellMichael J. KrashesJürgen WessNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Ken-ichiro Nakajima
Zhenzhong Cui
Chia Li
Jaroslawna Meister
Yinghong Cui
Ou Fu
Adam S. Smith
Shalini Jain
Bradford B. Lowell
Michael J. Krashes
Jürgen Wess
Gs-coupled GPCR signalling in AgRP neurons triggers sustained increase in food intake
description Hypothalamic Agouti-related peptide (AgRP) neurons play a key role in regulating food intake. Here, the authors report a novel pathway in which activation of Gs-coupled receptors on AgRP neurons leads to robust, sustained increase in food intake.
format article
author Ken-ichiro Nakajima
Zhenzhong Cui
Chia Li
Jaroslawna Meister
Yinghong Cui
Ou Fu
Adam S. Smith
Shalini Jain
Bradford B. Lowell
Michael J. Krashes
Jürgen Wess
author_facet Ken-ichiro Nakajima
Zhenzhong Cui
Chia Li
Jaroslawna Meister
Yinghong Cui
Ou Fu
Adam S. Smith
Shalini Jain
Bradford B. Lowell
Michael J. Krashes
Jürgen Wess
author_sort Ken-ichiro Nakajima
title Gs-coupled GPCR signalling in AgRP neurons triggers sustained increase in food intake
title_short Gs-coupled GPCR signalling in AgRP neurons triggers sustained increase in food intake
title_full Gs-coupled GPCR signalling in AgRP neurons triggers sustained increase in food intake
title_fullStr Gs-coupled GPCR signalling in AgRP neurons triggers sustained increase in food intake
title_full_unstemmed Gs-coupled GPCR signalling in AgRP neurons triggers sustained increase in food intake
title_sort gs-coupled gpcr signalling in agrp neurons triggers sustained increase in food intake
publisher Nature Portfolio
publishDate 2016
url https://doaj.org/article/d80731cbf6a5433fb3c995ee37ce1bac
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