Gs-coupled GPCR signalling in AgRP neurons triggers sustained increase in food intake
Hypothalamic Agouti-related peptide (AgRP) neurons play a key role in regulating food intake. Here, the authors report a novel pathway in which activation of Gs-coupled receptors on AgRP neurons leads to robust, sustained increase in food intake.
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Nature Portfolio
2016
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oai:doaj.org-article:d80731cbf6a5433fb3c995ee37ce1bac2021-12-02T17:31:49ZGs-coupled GPCR signalling in AgRP neurons triggers sustained increase in food intake10.1038/ncomms102682041-1723https://doaj.org/article/d80731cbf6a5433fb3c995ee37ce1bac2016-01-01T00:00:00Zhttps://doi.org/10.1038/ncomms10268https://doaj.org/toc/2041-1723Hypothalamic Agouti-related peptide (AgRP) neurons play a key role in regulating food intake. Here, the authors report a novel pathway in which activation of Gs-coupled receptors on AgRP neurons leads to robust, sustained increase in food intake.Ken-ichiro NakajimaZhenzhong CuiChia LiJaroslawna MeisterYinghong CuiOu FuAdam S. SmithShalini JainBradford B. LowellMichael J. KrashesJürgen WessNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-14 (2016) |
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DOAJ |
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EN |
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Science Q |
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Science Q Ken-ichiro Nakajima Zhenzhong Cui Chia Li Jaroslawna Meister Yinghong Cui Ou Fu Adam S. Smith Shalini Jain Bradford B. Lowell Michael J. Krashes Jürgen Wess Gs-coupled GPCR signalling in AgRP neurons triggers sustained increase in food intake |
description |
Hypothalamic Agouti-related peptide (AgRP) neurons play a key role in regulating food intake. Here, the authors report a novel pathway in which activation of Gs-coupled receptors on AgRP neurons leads to robust, sustained increase in food intake. |
format |
article |
author |
Ken-ichiro Nakajima Zhenzhong Cui Chia Li Jaroslawna Meister Yinghong Cui Ou Fu Adam S. Smith Shalini Jain Bradford B. Lowell Michael J. Krashes Jürgen Wess |
author_facet |
Ken-ichiro Nakajima Zhenzhong Cui Chia Li Jaroslawna Meister Yinghong Cui Ou Fu Adam S. Smith Shalini Jain Bradford B. Lowell Michael J. Krashes Jürgen Wess |
author_sort |
Ken-ichiro Nakajima |
title |
Gs-coupled GPCR signalling in AgRP neurons triggers sustained increase in food intake |
title_short |
Gs-coupled GPCR signalling in AgRP neurons triggers sustained increase in food intake |
title_full |
Gs-coupled GPCR signalling in AgRP neurons triggers sustained increase in food intake |
title_fullStr |
Gs-coupled GPCR signalling in AgRP neurons triggers sustained increase in food intake |
title_full_unstemmed |
Gs-coupled GPCR signalling in AgRP neurons triggers sustained increase in food intake |
title_sort |
gs-coupled gpcr signalling in agrp neurons triggers sustained increase in food intake |
publisher |
Nature Portfolio |
publishDate |
2016 |
url |
https://doaj.org/article/d80731cbf6a5433fb3c995ee37ce1bac |
work_keys_str_mv |
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