Neutralizing antibody responses to SARS-CoV-2 in symptomatic COVID-19 is persistent and critical for survival

Antibody responses are critical for protection from developing severe COVID-19 following SARS-CoV-2 infection. Here the authors show that antibody responses against SARS-CoV-2 spike protein correlate with neutralizing capacity and protection, are not affected by heterologous boosting of influenza or...

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Autores principales:	Stefania Dispinseri, Massimiliano Secchi, Maria Franca Pirillo, Monica Tolazzi, Martina Borghi, Cristina Brigatti, Maria Laura De Angelis, Marco Baratella, Elena Bazzigaluppi, Giulietta Venturi, Francesca Sironi, Andrea Canitano, Ilaria Marzinotto, Cristina Tresoldi, Fabio Ciceri, Lorenzo Piemonti, Donatella Negri, Andrea Cara, Vito Lampasona, Gabriella Scarlatti
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/d80ed3f91a004c7c8f240e8633323310
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spelling	oai:doaj.org-article:d80ed3f91a004c7c8f240e86333233102021-12-02T16:57:12ZNeutralizing antibody responses to SARS-CoV-2 in symptomatic COVID-19 is persistent and critical for survival10.1038/s41467-021-22958-82041-1723https://doaj.org/article/d80ed3f91a004c7c8f240e86333233102021-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-22958-8https://doaj.org/toc/2041-1723Antibody responses are critical for protection from developing severe COVID-19 following SARS-CoV-2 infection. Here the authors show that antibody responses against SARS-CoV-2 spike protein correlate with neutralizing capacity and protection, are not affected by heterologous boosting of influenza or common cold immunity, and can last up to 8 months.Stefania DispinseriMassimiliano SecchiMaria Franca PirilloMonica TolazziMartina BorghiCristina BrigattiMaria Laura De AngelisMarco BaratellaElena BazzigaluppiGiulietta VenturiFrancesca SironiAndrea CanitanoIlaria MarzinottoCristina TresoldiFabio CiceriLorenzo PiemontiDonatella NegriAndrea CaraVito LampasonaGabriella ScarlattiNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Stefania Dispinseri Massimiliano Secchi Maria Franca Pirillo Monica Tolazzi Martina Borghi Cristina Brigatti Maria Laura De Angelis Marco Baratella Elena Bazzigaluppi Giulietta Venturi Francesca Sironi Andrea Canitano Ilaria Marzinotto Cristina Tresoldi Fabio Ciceri Lorenzo Piemonti Donatella Negri Andrea Cara Vito Lampasona Gabriella Scarlatti Neutralizing antibody responses to SARS-CoV-2 in symptomatic COVID-19 is persistent and critical for survival
description	Antibody responses are critical for protection from developing severe COVID-19 following SARS-CoV-2 infection. Here the authors show that antibody responses against SARS-CoV-2 spike protein correlate with neutralizing capacity and protection, are not affected by heterologous boosting of influenza or common cold immunity, and can last up to 8 months.
format	article
author	Stefania Dispinseri Massimiliano Secchi Maria Franca Pirillo Monica Tolazzi Martina Borghi Cristina Brigatti Maria Laura De Angelis Marco Baratella Elena Bazzigaluppi Giulietta Venturi Francesca Sironi Andrea Canitano Ilaria Marzinotto Cristina Tresoldi Fabio Ciceri Lorenzo Piemonti Donatella Negri Andrea Cara Vito Lampasona Gabriella Scarlatti
author_facet	Stefania Dispinseri Massimiliano Secchi Maria Franca Pirillo Monica Tolazzi Martina Borghi Cristina Brigatti Maria Laura De Angelis Marco Baratella Elena Bazzigaluppi Giulietta Venturi Francesca Sironi Andrea Canitano Ilaria Marzinotto Cristina Tresoldi Fabio Ciceri Lorenzo Piemonti Donatella Negri Andrea Cara Vito Lampasona Gabriella Scarlatti
author_sort	Stefania Dispinseri
title	Neutralizing antibody responses to SARS-CoV-2 in symptomatic COVID-19 is persistent and critical for survival
title_short	Neutralizing antibody responses to SARS-CoV-2 in symptomatic COVID-19 is persistent and critical for survival
title_full	Neutralizing antibody responses to SARS-CoV-2 in symptomatic COVID-19 is persistent and critical for survival
title_fullStr	Neutralizing antibody responses to SARS-CoV-2 in symptomatic COVID-19 is persistent and critical for survival
title_full_unstemmed	Neutralizing antibody responses to SARS-CoV-2 in symptomatic COVID-19 is persistent and critical for survival
title_sort	neutralizing antibody responses to sars-cov-2 in symptomatic covid-19 is persistent and critical for survival
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/d80ed3f91a004c7c8f240e8633323310
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Neutralizing antibody responses to SARS-CoV-2 in symptomatic COVID-19 is persistent and critical for survival

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