How to Diagnose and Manage Angina Without Obstructive Coronary Artery Disease: Lessons from the British Heart Foundation CorMicA Trial

Patients with symptoms and/or signs of ischaemia but no obstructive coronary artery disease (INOCA) present a diagnostic and therapeutic challenge. Microvascular and/or vasospastic angina are the two most common causes of INOCA; however, invasive coronary angiography lacks the sensitivity to diagnos...

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Autores principales:	Thomas J Ford, Colin Berry
Formato:	article
Lenguaje:	EN
Publicado:	Radcliffe Medical Media 2019
Materias:	Surgery RD1-811 Diseases of the circulatory (Cardiovascular) system RC666-701
Acceso en línea:	https://doaj.org/article/d819c34941f54424adaf4f4631097584
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spelling	oai:doaj.org-article:d819c34941f54424adaf4f46310975842021-12-04T16:01:32ZHow to Diagnose and Manage Angina Without Obstructive Coronary Artery Disease: Lessons from the British Heart Foundation CorMicA Trial10.15420/icr.2019.04.R11756-14851756-1477https://doaj.org/article/d819c34941f54424adaf4f46310975842019-05-01T00:00:00Zhttps://www.icrjournal.com/articles/Angina-Without-Obstructive-CAD-BHF-CorMicA-Trialhttps://doaj.org/toc/1756-1477https://doaj.org/toc/1756-1485Patients with symptoms and/or signs of ischaemia but no obstructive coronary artery disease (INOCA) present a diagnostic and therapeutic challenge. Microvascular and/or vasospastic angina are the two most common causes of INOCA; however, invasive coronary angiography lacks the sensitivity to diagnose these functional coronary disorders. In this article, the authors summarise the rationale for invasive testing in the absence of obstructive coronary disease, namely that correct treatment for angina patients starts with the correct diagnosis. They provide insights from the CORonary MICrovascular Angina (CorMicA) study, where an interventional diagnostic procedure was performed with linked medical therapy to improve patient health. Identification of these distinct disorders (microvascular angina, vasospastic angina or non-cardiac chest pain) is key for stratifying INOCA patients, allowing prognostic insights and better patient care with linked therapy based on contemporary guidelines. Finally, they propose a framework to diagnose and manage patients in this common clinical scenario.Thomas J FordColin BerryRadcliffe Medical MediaarticleSurgeryRD1-811Diseases of the circulatory (Cardiovascular) systemRC666-701ENInterventional Cardiology: Reviews, Research, Resources, Vol 14, Iss 2, Pp 76-82 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Surgery RD1-811 Diseases of the circulatory (Cardiovascular) system RC666-701
spellingShingle	Surgery RD1-811 Diseases of the circulatory (Cardiovascular) system RC666-701 Thomas J Ford Colin Berry How to Diagnose and Manage Angina Without Obstructive Coronary Artery Disease: Lessons from the British Heart Foundation CorMicA Trial
description	Patients with symptoms and/or signs of ischaemia but no obstructive coronary artery disease (INOCA) present a diagnostic and therapeutic challenge. Microvascular and/or vasospastic angina are the two most common causes of INOCA; however, invasive coronary angiography lacks the sensitivity to diagnose these functional coronary disorders. In this article, the authors summarise the rationale for invasive testing in the absence of obstructive coronary disease, namely that correct treatment for angina patients starts with the correct diagnosis. They provide insights from the CORonary MICrovascular Angina (CorMicA) study, where an interventional diagnostic procedure was performed with linked medical therapy to improve patient health. Identification of these distinct disorders (microvascular angina, vasospastic angina or non-cardiac chest pain) is key for stratifying INOCA patients, allowing prognostic insights and better patient care with linked therapy based on contemporary guidelines. Finally, they propose a framework to diagnose and manage patients in this common clinical scenario.
format	article
author	Thomas J Ford Colin Berry
author_facet	Thomas J Ford Colin Berry
author_sort	Thomas J Ford
title	How to Diagnose and Manage Angina Without Obstructive Coronary Artery Disease: Lessons from the British Heart Foundation CorMicA Trial
title_short	How to Diagnose and Manage Angina Without Obstructive Coronary Artery Disease: Lessons from the British Heart Foundation CorMicA Trial
title_full	How to Diagnose and Manage Angina Without Obstructive Coronary Artery Disease: Lessons from the British Heart Foundation CorMicA Trial
title_fullStr	How to Diagnose and Manage Angina Without Obstructive Coronary Artery Disease: Lessons from the British Heart Foundation CorMicA Trial
title_full_unstemmed	How to Diagnose and Manage Angina Without Obstructive Coronary Artery Disease: Lessons from the British Heart Foundation CorMicA Trial
title_sort	how to diagnose and manage angina without obstructive coronary artery disease: lessons from the british heart foundation cormica trial
publisher	Radcliffe Medical Media
publishDate	2019
url	https://doaj.org/article/d819c34941f54424adaf4f4631097584
work_keys_str_mv	AT thomasjford howtodiagnoseandmanageanginawithoutobstructivecoronaryarterydiseaselessonsfromthebritishheartfoundationcormicatrial AT colinberry howtodiagnoseandmanageanginawithoutobstructivecoronaryarterydiseaselessonsfromthebritishheartfoundationcormicatrial
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How to Diagnose and Manage Angina Without Obstructive Coronary Artery Disease: Lessons from the British Heart Foundation CorMicA Trial

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