Increased risk of posterior circulation infarcts among ischemic stroke patients with cervical spondylosis

Chih-Chi Chen,1 Chia-Ying Chung,1 Tsong-Hai Lee,2 Wei-Han Chang,1 Simon FT Tang,1 Yu-Cheng Pei1,3 1Department of Physical Medicine and Rehabilitation, Chang Gung Memorial Hospital, Chang Gung University, College of Medicine, 2Department of Neurology, Chang Gung Memorial Hospital, Chang Gu...

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Autores principales:	Chen CC, Chung CY, Lee TH, Chang WH, Tang SF, Pei YC
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2015
Materias:	Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429
Acceso en línea:	https://doaj.org/article/d83377fb3bab4c8cbc64f94c7c714e18
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spelling	oai:doaj.org-article:d83377fb3bab4c8cbc64f94c7c714e182021-12-02T00:47:51ZIncreased risk of posterior circulation infarcts among ischemic stroke patients with cervical spondylosis1178-2021https://doaj.org/article/d83377fb3bab4c8cbc64f94c7c714e182015-02-01T00:00:00Zhttp://www.dovepress.com/increased-risk-of-posterior-circulation-infarcts-among-ischemic-stroke-peer-reviewed-article-NDThttps://doaj.org/toc/1178-2021 Chih-Chi Chen,1 Chia-Ying Chung,1 Tsong-Hai Lee,2 Wei-Han Chang,1 Simon FT Tang,1 Yu-Cheng Pei1,3 1Department of Physical Medicine and Rehabilitation, Chang Gung Memorial Hospital, Chang Gung University, College of Medicine, 2Department of Neurology, Chang Gung Memorial Hospital, Chang Gung University, College of Medicine, 3Healthy Aging Research Center, Chang Gung University, Taoyuan, Taiwan Background: Cervical spondylosis is one of the extrinsic factors causing vertebral artery stenosis. Several case studies have reported compression of the vertebral artery induced by cervical osteophytes that has resulted in posterior circulation infarcts (POCI). However, to the best of our knowledge, no studies have yet analyzed differences in the risk factors and stroke subtypes between ischemic stroke patients with cervical spondylosis and those without. Purpose: In the case-controlled study reported here, we analyzed the risk factors and stroke subtypes in ischemic stroke patients with and without cervical spondylosis. Characteristics in all the recruited patients with POCI and non-POCI were further compared to extract other risk factors that could predict the occurrence of POCI. Methods and patients: We filtered out ischemic stroke patients with cervical spondylosis (“Stroke+C” group) by International Classification of Diseases, Ninth Revision codes. We analyzed the data of 38 subjects in the Stroke+C group and 152 sex- and age-comparable ischemic stroke patients without cervical spondylosis (“Stroke-C” group). We recorded the demographic characteristics including sex and age, and stroke risk factors, including diabetes mellitus, hypertension, heart disease, hyperlipidemia, and smoking habits. The stroke classifications were defined by the Oxford Community Stroke Project classification. All subjects were further categorized into POCI or non-POCI groups. The ultrasound findings of the vertebral arteries (extracranial and intracranial) in the Stroke+C group were also recorded. Results: More patients in the Stroke+C group tended to have POCI (34.2%) than patients in the Stroke-C group (17.5%) (odds ratio [OR] =2.41, P<0.05). Furthermore, hypertension (OR=3.41, P<0.01) and cervical spondylosis (OR=2.41, P<0.05) were two independent risk factors for POCI in ischemic stroke patients. Conclusion: Ischemic stroke patients with cervical spondylosis are more prone to POCI than those without cervical spondylosis. Hypertension is another identified risk factor for POCI in ischemic stroke patients. The occurrence of POCI should be highlighted for patients with cervical spondylosis. Keywords: risk factors, vertebral artery stenosis, cervical osteophytesChen CCChung CYLee THChang WHTang SFPei YCDove Medical PressarticleNeurosciences. Biological psychiatry. NeuropsychiatryRC321-571Neurology. Diseases of the nervous systemRC346-429ENNeuropsychiatric Disease and Treatment, Vol 2015, Iss default, Pp 273-278 (2015)
institution	DOAJ
collection	DOAJ
language	EN
topic	Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429
spellingShingle	Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429 Chen CC Chung CY Lee TH Chang WH Tang SF Pei YC Increased risk of posterior circulation infarcts among ischemic stroke patients with cervical spondylosis
description	Chih-Chi Chen,1 Chia-Ying Chung,1 Tsong-Hai Lee,2 Wei-Han Chang,1 Simon FT Tang,1 Yu-Cheng Pei1,3 1Department of Physical Medicine and Rehabilitation, Chang Gung Memorial Hospital, Chang Gung University, College of Medicine, 2Department of Neurology, Chang Gung Memorial Hospital, Chang Gung University, College of Medicine, 3Healthy Aging Research Center, Chang Gung University, Taoyuan, Taiwan Background: Cervical spondylosis is one of the extrinsic factors causing vertebral artery stenosis. Several case studies have reported compression of the vertebral artery induced by cervical osteophytes that has resulted in posterior circulation infarcts (POCI). However, to the best of our knowledge, no studies have yet analyzed differences in the risk factors and stroke subtypes between ischemic stroke patients with cervical spondylosis and those without. Purpose: In the case-controlled study reported here, we analyzed the risk factors and stroke subtypes in ischemic stroke patients with and without cervical spondylosis. Characteristics in all the recruited patients with POCI and non-POCI were further compared to extract other risk factors that could predict the occurrence of POCI. Methods and patients: We filtered out ischemic stroke patients with cervical spondylosis (“Stroke+C” group) by International Classification of Diseases, Ninth Revision codes. We analyzed the data of 38 subjects in the Stroke+C group and 152 sex- and age-comparable ischemic stroke patients without cervical spondylosis (“Stroke-C” group). We recorded the demographic characteristics including sex and age, and stroke risk factors, including diabetes mellitus, hypertension, heart disease, hyperlipidemia, and smoking habits. The stroke classifications were defined by the Oxford Community Stroke Project classification. All subjects were further categorized into POCI or non-POCI groups. The ultrasound findings of the vertebral arteries (extracranial and intracranial) in the Stroke+C group were also recorded. Results: More patients in the Stroke+C group tended to have POCI (34.2%) than patients in the Stroke-C group (17.5%) (odds ratio [OR] =2.41, P<0.05). Furthermore, hypertension (OR=3.41, P<0.01) and cervical spondylosis (OR=2.41, P<0.05) were two independent risk factors for POCI in ischemic stroke patients. Conclusion: Ischemic stroke patients with cervical spondylosis are more prone to POCI than those without cervical spondylosis. Hypertension is another identified risk factor for POCI in ischemic stroke patients. The occurrence of POCI should be highlighted for patients with cervical spondylosis. Keywords: risk factors, vertebral artery stenosis, cervical osteophytes
format	article
author	Chen CC Chung CY Lee TH Chang WH Tang SF Pei YC
author_facet	Chen CC Chung CY Lee TH Chang WH Tang SF Pei YC
author_sort	Chen CC
title	Increased risk of posterior circulation infarcts among ischemic stroke patients with cervical spondylosis
title_short	Increased risk of posterior circulation infarcts among ischemic stroke patients with cervical spondylosis
title_full	Increased risk of posterior circulation infarcts among ischemic stroke patients with cervical spondylosis
title_fullStr	Increased risk of posterior circulation infarcts among ischemic stroke patients with cervical spondylosis
title_full_unstemmed	Increased risk of posterior circulation infarcts among ischemic stroke patients with cervical spondylosis
title_sort	increased risk of posterior circulation infarcts among ischemic stroke patients with cervical spondylosis
publisher	Dove Medical Press
publishDate	2015
url	https://doaj.org/article/d83377fb3bab4c8cbc64f94c7c714e18
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Increased risk of posterior circulation infarcts among ischemic stroke patients with cervical spondylosis

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