Sphingosine 1-phosphate modulates antigen capture by murine Langerhans cells via the S1P2 receptor subtype.
Dendritic cells (DCs) play a pivotal role in the development of cutaneous contact hypersensitivity (CHS) and atopic dermatitis as they capture and process antigen and present it to T lymphocytes in the lymphoid organs. Recently, it has been indicated that a topical application of the sphingolipid sp...
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Main Authors: | Lukasz Japtok, Katrin Schaper, Wolfgang Bäumer, Heinfried H Radeke, Se Kyoo Jeong, Burkhard Kleuser |
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Format: | article |
Language: | EN |
Published: |
Public Library of Science (PLoS)
2012
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Online Access: | https://doaj.org/article/d84a7388d2544e6fbabb56379a2b57a4 |
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