A lysozyme with altered substrate specificity facilitates prey cell exit by the periplasmic predator Bdellovibrio bacteriovorus

The bacterial periplasmic predator Bdellovibrio bacteriovorus deacetylates the peptidoglycan of the prey bacterium early upon invasion. Here, the authors identify and characterize a Bdellovibrio lysozyme that acts specifically on deacetylated peptidoglycan and is important for periplasmic exit.

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Autores principales:	Christopher J. Harding, Simona G. Huwiler, Hannah Somers, Carey Lambert, Luke J. Ray, Rob Till, Georgina Taylor, Patrick J. Moynihan, R. Elizabeth Sockett, Andrew L. Lovering
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/d84ea87864944e33943ceb0260130cf0
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spelling	oai:doaj.org-article:d84ea87864944e33943ceb0260130cf02021-12-02T17:27:20ZA lysozyme with altered substrate specificity facilitates prey cell exit by the periplasmic predator Bdellovibrio bacteriovorus10.1038/s41467-020-18139-82041-1723https://doaj.org/article/d84ea87864944e33943ceb0260130cf02020-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-18139-8https://doaj.org/toc/2041-1723The bacterial periplasmic predator Bdellovibrio bacteriovorus deacetylates the peptidoglycan of the prey bacterium early upon invasion. Here, the authors identify and characterize a Bdellovibrio lysozyme that acts specifically on deacetylated peptidoglycan and is important for periplasmic exit.Christopher J. HardingSimona G. HuwilerHannah SomersCarey LambertLuke J. RayRob TillGeorgina TaylorPatrick J. MoynihanR. Elizabeth SockettAndrew L. LoveringNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Christopher J. Harding Simona G. Huwiler Hannah Somers Carey Lambert Luke J. Ray Rob Till Georgina Taylor Patrick J. Moynihan R. Elizabeth Sockett Andrew L. Lovering A lysozyme with altered substrate specificity facilitates prey cell exit by the periplasmic predator Bdellovibrio bacteriovorus
description	The bacterial periplasmic predator Bdellovibrio bacteriovorus deacetylates the peptidoglycan of the prey bacterium early upon invasion. Here, the authors identify and characterize a Bdellovibrio lysozyme that acts specifically on deacetylated peptidoglycan and is important for periplasmic exit.
format	article
author	Christopher J. Harding Simona G. Huwiler Hannah Somers Carey Lambert Luke J. Ray Rob Till Georgina Taylor Patrick J. Moynihan R. Elizabeth Sockett Andrew L. Lovering
author_facet	Christopher J. Harding Simona G. Huwiler Hannah Somers Carey Lambert Luke J. Ray Rob Till Georgina Taylor Patrick J. Moynihan R. Elizabeth Sockett Andrew L. Lovering
author_sort	Christopher J. Harding
title	A lysozyme with altered substrate specificity facilitates prey cell exit by the periplasmic predator Bdellovibrio bacteriovorus
title_short	A lysozyme with altered substrate specificity facilitates prey cell exit by the periplasmic predator Bdellovibrio bacteriovorus
title_full	A lysozyme with altered substrate specificity facilitates prey cell exit by the periplasmic predator Bdellovibrio bacteriovorus
title_fullStr	A lysozyme with altered substrate specificity facilitates prey cell exit by the periplasmic predator Bdellovibrio bacteriovorus
title_full_unstemmed	A lysozyme with altered substrate specificity facilitates prey cell exit by the periplasmic predator Bdellovibrio bacteriovorus
title_sort	lysozyme with altered substrate specificity facilitates prey cell exit by the periplasmic predator bdellovibrio bacteriovorus
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/d84ea87864944e33943ceb0260130cf0
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A lysozyme with altered substrate specificity facilitates prey cell exit by the periplasmic predator Bdellovibrio bacteriovorus

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