<i>miR-31</i>-<i>NUMB</i> Cascade Modulates Monocarboxylate Transporters to Increase Oncogenicity and Lactate Production of Oral Carcinoma Cells

<i>miR-31</i>-<i>NUMB</i> Cascade Modulates Monocarboxylate Transporters to Increase Oncogenicity and Lactate Production of Oral Carcinoma Cells

Oral squamous cell carcinoma (OSCC) is among the leading causes of cancer-associated death worldwide. <i>miR-31</i> is an oncogenic miRNA in OSCC. NUMB is an adaptor protein capable of suppressing malignant transformation. Disruption of the <i>miR-31</i>-<i>NUMB</i&g...

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Detalles Bibliográficos
Autores principales: Chung-Hsien Chou, Chun-Yu Fan Chiang, Cheng-Chieh Yang, Ying-Chieh Liu, Sih-Rou Chang, Kuo-Wei Chang, Shu-Chun Lin
Formato: article
Lenguaje:EN
Publicado: MDPI AG 2021
Materias:
CRISPR
lactate
<i>MCT1</i>
<i>MCT4</i>
<i>miR-31</i>
<i>NUMB</i>
Biology (General)
QH301-705.5
Chemistry
QD1-999
Acceso en línea:https://doaj.org/article/d858cb94452b47c89ce80db39bb95cb9
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