Multiomic analysis of the Arabian camel (Camelus dromedarius) kidney reveals a role for cholesterol in water conservation

Fernando Alvira-Iraizoz and Benjamin T. Gillard et al. comprehensively catalogue the kidney transcriptome and proteome of dromedary camels in response to chronic dehydration stress and subsequent acute rehydration. Their results suggest that the suppression of the cholesterol biosynthesis may facili...

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Autores principales:	Fernando Alvira-Iraizoz, Benjamin T. Gillard, Panjiao Lin, Alex Paterson, Audrys G. Pauža, Mahmoud A. Ali, Ammar H. Alabsi, Pamela A. Burger, Naserddine Hamadi, Abdu Adem, David Murphy, Michael P. Greenwood
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/d8616ab913bc4af5a29d5f269a823c7b
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spelling	oai:doaj.org-article:d8616ab913bc4af5a29d5f269a823c7b2021-12-02T16:05:53ZMultiomic analysis of the Arabian camel (Camelus dromedarius) kidney reveals a role for cholesterol in water conservation10.1038/s42003-021-02327-32399-3642https://doaj.org/article/d8616ab913bc4af5a29d5f269a823c7b2021-06-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-02327-3https://doaj.org/toc/2399-3642Fernando Alvira-Iraizoz and Benjamin T. Gillard et al. comprehensively catalogue the kidney transcriptome and proteome of dromedary camels in response to chronic dehydration stress and subsequent acute rehydration. Their results suggest that the suppression of the cholesterol biosynthesis may facilitate water retention in the dromedary camel kidney, providing further insight into how these animals survive in arid conditions.Fernando Alvira-IraizozBenjamin T. GillardPanjiao LinAlex PatersonAudrys G. PaužaMahmoud A. AliAmmar H. AlabsiPamela A. BurgerNaserddine HamadiAbdu AdemDavid MurphyMichael P. GreenwoodNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-21 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Biology (General) QH301-705.5
spellingShingle	Biology (General) QH301-705.5 Fernando Alvira-Iraizoz Benjamin T. Gillard Panjiao Lin Alex Paterson Audrys G. Pauža Mahmoud A. Ali Ammar H. Alabsi Pamela A. Burger Naserddine Hamadi Abdu Adem David Murphy Michael P. Greenwood Multiomic analysis of the Arabian camel (Camelus dromedarius) kidney reveals a role for cholesterol in water conservation
description	Fernando Alvira-Iraizoz and Benjamin T. Gillard et al. comprehensively catalogue the kidney transcriptome and proteome of dromedary camels in response to chronic dehydration stress and subsequent acute rehydration. Their results suggest that the suppression of the cholesterol biosynthesis may facilitate water retention in the dromedary camel kidney, providing further insight into how these animals survive in arid conditions.
format	article
author	Fernando Alvira-Iraizoz Benjamin T. Gillard Panjiao Lin Alex Paterson Audrys G. Pauža Mahmoud A. Ali Ammar H. Alabsi Pamela A. Burger Naserddine Hamadi Abdu Adem David Murphy Michael P. Greenwood
author_facet	Fernando Alvira-Iraizoz Benjamin T. Gillard Panjiao Lin Alex Paterson Audrys G. Pauža Mahmoud A. Ali Ammar H. Alabsi Pamela A. Burger Naserddine Hamadi Abdu Adem David Murphy Michael P. Greenwood
author_sort	Fernando Alvira-Iraizoz
title	Multiomic analysis of the Arabian camel (Camelus dromedarius) kidney reveals a role for cholesterol in water conservation
title_short	Multiomic analysis of the Arabian camel (Camelus dromedarius) kidney reveals a role for cholesterol in water conservation
title_full	Multiomic analysis of the Arabian camel (Camelus dromedarius) kidney reveals a role for cholesterol in water conservation
title_fullStr	Multiomic analysis of the Arabian camel (Camelus dromedarius) kidney reveals a role for cholesterol in water conservation
title_full_unstemmed	Multiomic analysis of the Arabian camel (Camelus dromedarius) kidney reveals a role for cholesterol in water conservation
title_sort	multiomic analysis of the arabian camel (camelus dromedarius) kidney reveals a role for cholesterol in water conservation
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/d8616ab913bc4af5a29d5f269a823c7b
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Multiomic analysis of the Arabian camel (Camelus dromedarius) kidney reveals a role for cholesterol in water conservation

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