Engineering yeast hexokinase 2 for improved tolerance toward xylose-induced inactivation.
Hexokinase 2 (Hxk2p) from Saccharomyces cerevisiae is a bi-functional enzyme being both a catalyst and an important regulator in the glucose repression signal. In the presence of xylose Hxk2p is irreversibly inactivated through an autophosphorylation mechanism, affecting all functions. Consequently,...
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Autores principales: | Basti Bergdahl, Anders G Sandström, Celina Borgström, Tarinee Boonyawan, Ed W J van Niel, Marie F Gorwa-Grauslund |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2013
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Materias: | |
Acceso en línea: | https://doaj.org/article/d866290bca7a4d60963f074c389649e6 |
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