RNF115 plays dual roles in innate antiviral responses by catalyzing distinct ubiquitination of MAVS and MITA

MAVS and MITA are adapter proteins that play distinct roles in the context of the host response to RNA and DNA viruses, respectively. Here the authors implicate RNF115 in dual temporal and spatial mechanisms of interacting and catalyzing distinct ubiquitination of MAVS and MITA to modulate RNA and D...

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Autores principales:	Zhi-Dong Zhang, Tian-Chen Xiong, Shu-Qi Yao, Ming-Cong Wei, Ming Chen, Dandan Lin, Bo Zhong
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/d86849cb360d49c3b4f0cb43df17139e
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spelling	oai:doaj.org-article:d86849cb360d49c3b4f0cb43df17139e2021-12-02T15:39:12ZRNF115 plays dual roles in innate antiviral responses by catalyzing distinct ubiquitination of MAVS and MITA10.1038/s41467-020-19318-32041-1723https://doaj.org/article/d86849cb360d49c3b4f0cb43df17139e2020-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-19318-3https://doaj.org/toc/2041-1723MAVS and MITA are adapter proteins that play distinct roles in the context of the host response to RNA and DNA viruses, respectively. Here the authors implicate RNF115 in dual temporal and spatial mechanisms of interacting and catalyzing distinct ubiquitination of MAVS and MITA to modulate RNA and DNA antiviral immune responses.Zhi-Dong ZhangTian-Chen XiongShu-Qi YaoMing-Cong WeiMing ChenDandan LinBo ZhongNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Zhi-Dong Zhang Tian-Chen Xiong Shu-Qi Yao Ming-Cong Wei Ming Chen Dandan Lin Bo Zhong RNF115 plays dual roles in innate antiviral responses by catalyzing distinct ubiquitination of MAVS and MITA
description	MAVS and MITA are adapter proteins that play distinct roles in the context of the host response to RNA and DNA viruses, respectively. Here the authors implicate RNF115 in dual temporal and spatial mechanisms of interacting and catalyzing distinct ubiquitination of MAVS and MITA to modulate RNA and DNA antiviral immune responses.
format	article
author	Zhi-Dong Zhang Tian-Chen Xiong Shu-Qi Yao Ming-Cong Wei Ming Chen Dandan Lin Bo Zhong
author_facet	Zhi-Dong Zhang Tian-Chen Xiong Shu-Qi Yao Ming-Cong Wei Ming Chen Dandan Lin Bo Zhong
author_sort	Zhi-Dong Zhang
title	RNF115 plays dual roles in innate antiviral responses by catalyzing distinct ubiquitination of MAVS and MITA
title_short	RNF115 plays dual roles in innate antiviral responses by catalyzing distinct ubiquitination of MAVS and MITA
title_full	RNF115 plays dual roles in innate antiviral responses by catalyzing distinct ubiquitination of MAVS and MITA
title_fullStr	RNF115 plays dual roles in innate antiviral responses by catalyzing distinct ubiquitination of MAVS and MITA
title_full_unstemmed	RNF115 plays dual roles in innate antiviral responses by catalyzing distinct ubiquitination of MAVS and MITA
title_sort	rnf115 plays dual roles in innate antiviral responses by catalyzing distinct ubiquitination of mavs and mita
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/d86849cb360d49c3b4f0cb43df17139e
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RNF115 plays dual roles in innate antiviral responses by catalyzing distinct ubiquitination of MAVS and MITA

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