Aggregated transthyretin is specifically packaged into placental nano-vesicles in preeclampsia
Abstract In preeclampsia, the serum levels of transthyretin, a carrier protein for thyroxine, are elevated. Transthyretin isolated from preeclamptic serum is also aggregated and can induce preeclampsia-like symptoms in pregnant IL10−/− mice. Using western blotting, immunofluorescence, ELISA and qRT-...
Guardado en:
Autores principales: | Mancy Tong, Shi-bin Cheng, Qi Chen, Joana DeSousa, Peter R. Stone, Joanna L. James, Lawrence W. Chamley, Surendra Sharma |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2017
|
Materias: | |
Acceso en línea: | https://doaj.org/article/d86da9a98d17490480dbca830c152fcc |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Stochastic master equation for early protein aggregation in the transthyretin amyloid disease
por: Ruo-Nan Liu, et al.
Publicado: (2020) -
Ultrastructural and Immunohistochemical Features of Telocytes in Placental Villi in Preeclampsia
por: Natalia V. Nizyaeva, et al.
Publicado: (2018) -
Association between proteinuria and placental pathology in preeclampsia: A retrospective study
por: Dominique Suzanne Genest, et al.
Publicado: (2021) -
Transthyretin Promotes Axon Growth via Regulation of Microtubule Dynamics and Tubulin Acetylation
por: Jessica Eira, et al.
Publicado: (2021) -
Integrins mediate placental extracellular vesicle trafficking to lung and liver in vivo
por: Sean L. Nguyen, et al.
Publicado: (2021)