Human skin aging is associated with increased expression of the histone variant H2A.J in the epidermis
Abstract Cellular senescence is an irreversible growth arrest that occurs as a result of damaging stimuli, including DNA damage and/or telomere shortening. Here, we investigate histone variant H2A.J as a new biomarker to detect senescent cells during human skin aging. Skin biopsies from healthy volu...
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Autores principales: | Claudia E. Rübe, Caroline Bäumert, Nadine Schuler, Anna Isermann, Zoé Schmal, Matthias Glanemann, Carl Mann, Harry Scherthan |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/d87dc7743f364e58867d576df1284703 |
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