Entropy measures quantify global splicing disorders in cancer.

Most mammalian genes are able to express several splice variants in a phenomenon known as alternative splicing. Serious alterations of alternative splicing occur in cancer tissues, leading to expression of multiple aberrant splice forms. Most studies of alternative splicing defects have focused on t...

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Autores principales: William Ritchie, Samuel Granjeaud, Denis Puthier, Daniel Gautheret
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2008
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Acceso en línea:https://doaj.org/article/d886706782b84fa8b4c3d3b123862386
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