Neural mechanisms of contextual modulation in the retinal direction selective circuit
The mechanisms of contextual modulation in direction selective ganglion cells in the retina remain unclear. Here, the authors find that that On-Off direction-selective ganglion cells are differentially sensitive to discontinuities of dark and bright moving edges in the visual environment and, using...
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Nature Portfolio
2019
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oai:doaj.org-article:d88967dd20f44d26bf598cccde8116662021-12-02T15:35:09ZNeural mechanisms of contextual modulation in the retinal direction selective circuit10.1038/s41467-019-10268-z2041-1723https://doaj.org/article/d88967dd20f44d26bf598cccde8116662019-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-10268-zhttps://doaj.org/toc/2041-1723The mechanisms of contextual modulation in direction selective ganglion cells in the retina remain unclear. Here, the authors find that that On-Off direction-selective ganglion cells are differentially sensitive to discontinuities of dark and bright moving edges in the visual environment and, using synapse-specific genetic manipulations with functional measurements, reveal the microcircuits underlying this contextual sensitivity.Xiaolin HuangMelissa RangelKevin L. BriggmanWei WeiNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-15 (2019) |
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Science Q Xiaolin Huang Melissa Rangel Kevin L. Briggman Wei Wei Neural mechanisms of contextual modulation in the retinal direction selective circuit |
description |
The mechanisms of contextual modulation in direction selective ganglion cells in the retina remain unclear. Here, the authors find that that On-Off direction-selective ganglion cells are differentially sensitive to discontinuities of dark and bright moving edges in the visual environment and, using synapse-specific genetic manipulations with functional measurements, reveal the microcircuits underlying this contextual sensitivity. |
format |
article |
author |
Xiaolin Huang Melissa Rangel Kevin L. Briggman Wei Wei |
author_facet |
Xiaolin Huang Melissa Rangel Kevin L. Briggman Wei Wei |
author_sort |
Xiaolin Huang |
title |
Neural mechanisms of contextual modulation in the retinal direction selective circuit |
title_short |
Neural mechanisms of contextual modulation in the retinal direction selective circuit |
title_full |
Neural mechanisms of contextual modulation in the retinal direction selective circuit |
title_fullStr |
Neural mechanisms of contextual modulation in the retinal direction selective circuit |
title_full_unstemmed |
Neural mechanisms of contextual modulation in the retinal direction selective circuit |
title_sort |
neural mechanisms of contextual modulation in the retinal direction selective circuit |
publisher |
Nature Portfolio |
publishDate |
2019 |
url |
https://doaj.org/article/d88967dd20f44d26bf598cccde811666 |
work_keys_str_mv |
AT xiaolinhuang neuralmechanismsofcontextualmodulationintheretinaldirectionselectivecircuit AT melissarangel neuralmechanismsofcontextualmodulationintheretinaldirectionselectivecircuit AT kevinlbriggman neuralmechanismsofcontextualmodulationintheretinaldirectionselectivecircuit AT weiwei neuralmechanismsofcontextualmodulationintheretinaldirectionselectivecircuit |
_version_ |
1718386688347078656 |