Neural mechanisms of contextual modulation in the retinal direction selective circuit

The mechanisms of contextual modulation in direction selective ganglion cells in the retina remain unclear. Here, the authors find that that On-Off direction-selective ganglion cells are differentially sensitive to discontinuities of dark and bright moving edges in the visual environment and, using...

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Autores principales: Xiaolin Huang, Melissa Rangel, Kevin L. Briggman, Wei Wei
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/d88967dd20f44d26bf598cccde811666
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spelling oai:doaj.org-article:d88967dd20f44d26bf598cccde8116662021-12-02T15:35:09ZNeural mechanisms of contextual modulation in the retinal direction selective circuit10.1038/s41467-019-10268-z2041-1723https://doaj.org/article/d88967dd20f44d26bf598cccde8116662019-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-10268-zhttps://doaj.org/toc/2041-1723The mechanisms of contextual modulation in direction selective ganglion cells in the retina remain unclear. Here, the authors find that that On-Off direction-selective ganglion cells are differentially sensitive to discontinuities of dark and bright moving edges in the visual environment and, using synapse-specific genetic manipulations with functional measurements, reveal the microcircuits underlying this contextual sensitivity.Xiaolin HuangMelissa RangelKevin L. BriggmanWei WeiNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Xiaolin Huang
Melissa Rangel
Kevin L. Briggman
Wei Wei
Neural mechanisms of contextual modulation in the retinal direction selective circuit
description The mechanisms of contextual modulation in direction selective ganglion cells in the retina remain unclear. Here, the authors find that that On-Off direction-selective ganglion cells are differentially sensitive to discontinuities of dark and bright moving edges in the visual environment and, using synapse-specific genetic manipulations with functional measurements, reveal the microcircuits underlying this contextual sensitivity.
format article
author Xiaolin Huang
Melissa Rangel
Kevin L. Briggman
Wei Wei
author_facet Xiaolin Huang
Melissa Rangel
Kevin L. Briggman
Wei Wei
author_sort Xiaolin Huang
title Neural mechanisms of contextual modulation in the retinal direction selective circuit
title_short Neural mechanisms of contextual modulation in the retinal direction selective circuit
title_full Neural mechanisms of contextual modulation in the retinal direction selective circuit
title_fullStr Neural mechanisms of contextual modulation in the retinal direction selective circuit
title_full_unstemmed Neural mechanisms of contextual modulation in the retinal direction selective circuit
title_sort neural mechanisms of contextual modulation in the retinal direction selective circuit
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/d88967dd20f44d26bf598cccde811666
work_keys_str_mv AT xiaolinhuang neuralmechanismsofcontextualmodulationintheretinaldirectionselectivecircuit
AT melissarangel neuralmechanismsofcontextualmodulationintheretinaldirectionselectivecircuit
AT kevinlbriggman neuralmechanismsofcontextualmodulationintheretinaldirectionselectivecircuit
AT weiwei neuralmechanismsofcontextualmodulationintheretinaldirectionselectivecircuit
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