Metabolic modelling reveals the specialization of secondary replicons for niche adaptation in Sinorhizobium meliloti

The genome of some bacteria consists of two or more chromosomes or replicons. Here, diCenzo et al. integrate genome-scale metabolic modelling and growth data from a collection of mutants of the plant symbiont Sinorhizobium melilotito estimate the fitness contribution of each replicon in three enviro...

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Main Authors:	George C. diCenzo, Alice Checcucci, Marco Bazzicalupo, Alessio Mengoni, Carlo Viti, Lukasz Dziewit, Turlough M. Finan, Marco Galardini, Marco Fondi
Format:	article
Language:	EN
Published:	Nature Portfolio 2016
Subjects:	Science Q
Online Access:	https://doaj.org/article/d88cc4dd211a489280d7429037268cff
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id	oai:doaj.org-article:d88cc4dd211a489280d7429037268cff
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spelling	oai:doaj.org-article:d88cc4dd211a489280d7429037268cff2021-12-02T14:39:14ZMetabolic modelling reveals the specialization of secondary replicons for niche adaptation in Sinorhizobium meliloti10.1038/ncomms122192041-1723https://doaj.org/article/d88cc4dd211a489280d7429037268cff2016-07-01T00:00:00Zhttps://doi.org/10.1038/ncomms12219https://doaj.org/toc/2041-1723The genome of some bacteria consists of two or more chromosomes or replicons. Here, diCenzo et al. integrate genome-scale metabolic modelling and growth data from a collection of mutants of the plant symbiont Sinorhizobium melilotito estimate the fitness contribution of each replicon in three environments.George C. diCenzoAlice CheccucciMarco BazzicalupoAlessio MengoniCarlo VitiLukasz DziewitTurlough M. FinanMarco GalardiniMarco FondiNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-10 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q George C. diCenzo Alice Checcucci Marco Bazzicalupo Alessio Mengoni Carlo Viti Lukasz Dziewit Turlough M. Finan Marco Galardini Marco Fondi Metabolic modelling reveals the specialization of secondary replicons for niche adaptation in Sinorhizobium meliloti
description	The genome of some bacteria consists of two or more chromosomes or replicons. Here, diCenzo et al. integrate genome-scale metabolic modelling and growth data from a collection of mutants of the plant symbiont Sinorhizobium melilotito estimate the fitness contribution of each replicon in three environments.
format	article
author	George C. diCenzo Alice Checcucci Marco Bazzicalupo Alessio Mengoni Carlo Viti Lukasz Dziewit Turlough M. Finan Marco Galardini Marco Fondi
author_facet	George C. diCenzo Alice Checcucci Marco Bazzicalupo Alessio Mengoni Carlo Viti Lukasz Dziewit Turlough M. Finan Marco Galardini Marco Fondi
author_sort	George C. diCenzo
title	Metabolic modelling reveals the specialization of secondary replicons for niche adaptation in Sinorhizobium meliloti
title_short	Metabolic modelling reveals the specialization of secondary replicons for niche adaptation in Sinorhizobium meliloti
title_full	Metabolic modelling reveals the specialization of secondary replicons for niche adaptation in Sinorhizobium meliloti
title_fullStr	Metabolic modelling reveals the specialization of secondary replicons for niche adaptation in Sinorhizobium meliloti
title_full_unstemmed	Metabolic modelling reveals the specialization of secondary replicons for niche adaptation in Sinorhizobium meliloti
title_sort	metabolic modelling reveals the specialization of secondary replicons for niche adaptation in sinorhizobium meliloti
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/d88cc4dd211a489280d7429037268cff
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Metabolic modelling reveals the specialization of secondary replicons for niche adaptation in Sinorhizobium meliloti

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