Instructions for Flow Cytometric Detection of ASC Specks as a Readout of Inflammasome Activation in Human Blood
Inflammasome activation is linked to the aggregation of the adaptor protein ASC into a multiprotein complex, known as the ASC speck. Redistribution of cytosolic ASC to this complex has been widely used as a readout for inflammasome activation and precedes the downstream proteolytic release of the pr...
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Auteurs principaux: | Nico Wittmann, Ann-Kathrin Behrendt, Neha Mishra, Lukas Bossaller, Almut Meyer-Bahlburg |
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Format: | article |
Langue: | EN |
Publié: |
MDPI AG
2021
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Accès en ligne: | https://doaj.org/article/d88e83223c05471d9d77568b3e1df41c |
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