Clostridium perfringens epsilon toxin targets granule cells in the mouse cerebellum and stimulates glutamate release.

Epsilon toxin (ET) produced by C. perfringens types B and D is a highly potent pore-forming toxin. ET-intoxicated animals express severe neurological disorders that are thought to result from the formation of vasogenic brain edemas and indirect neuronal excitotoxicity. The cerebellum is a predilecti...

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Autores principales: Etienne Lonchamp, Jean-Luc Dupont, Laetitia Wioland, Raphaël Courjaret, Corinne Mbebi-Liegeois, Emmanuel Jover, Frédéric Doussau, Michel R Popoff, Jean-Louis Bossu, Jean de Barry, Bernard Poulain
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2010
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Acceso en línea:https://doaj.org/article/d8915b8ca71749f7a48be7d3dd3969ce
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