Clostridium perfringens epsilon toxin targets granule cells in the mouse cerebellum and stimulates glutamate release.
Epsilon toxin (ET) produced by C. perfringens types B and D is a highly potent pore-forming toxin. ET-intoxicated animals express severe neurological disorders that are thought to result from the formation of vasogenic brain edemas and indirect neuronal excitotoxicity. The cerebellum is a predilecti...
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Autores principales: | Etienne Lonchamp, Jean-Luc Dupont, Laetitia Wioland, Raphaël Courjaret, Corinne Mbebi-Liegeois, Emmanuel Jover, Frédéric Doussau, Michel R Popoff, Jean-Louis Bossu, Jean de Barry, Bernard Poulain |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2010
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Materias: | |
Acceso en línea: | https://doaj.org/article/d8915b8ca71749f7a48be7d3dd3969ce |
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