Antiphospholipid syndrome in lupus retinopathy

Ng Hong-Kee,1,2 Chong Mei-Fong,2 Yaakub Azhany,1 Embong Zunaina1 1Department of Ophthalmology, School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian, Kelantan, Malaysia; 2Department of Ophthalmology, Hospital Raja Permaisuri Bainun, Ipoh, Perak, Malaysia Abstract: Systemic lupus er...

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Autores principales:	Hong-Kee N, Mei-Fong C, Azhany Y, Zunaina E
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2014
Materias:	Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/d89f6d618ebe4939b7ffaec61546e7b5
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spelling	oai:doaj.org-article:d89f6d618ebe4939b7ffaec61546e7b52021-12-02T02:06:44ZAntiphospholipid syndrome in lupus retinopathy1177-5483https://doaj.org/article/d89f6d618ebe4939b7ffaec61546e7b52014-11-01T00:00:00Zhttp://www.dovepress.com/antiphospholipid-syndrome-in-lupus-retinopathy-peer-reviewed-article-OPTHhttps://doaj.org/toc/1177-5483 Ng Hong-Kee,1,2 Chong Mei-Fong,2 Yaakub Azhany,1 Embong Zunaina1 1Department of Ophthalmology, School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian, Kelantan, Malaysia; 2Department of Ophthalmology, Hospital Raja Permaisuri Bainun, Ipoh, Perak, Malaysia Abstract: Systemic lupus erythematosus (SLE) is a chronic, multisystem, autoimmune disease that can affect any part of the human body including the eyes. Common blinding ocular manifestations include central retinal artery occlusion (CRAO), central retinal vein occlusion (CRVO), severe vaso-occlusive retinopathy, and optic nerve involvement. Antiphospholipid syndrome (APS) in lupus is usually associated with large vessel occlusions and needs prompt treatment with anticoagulant. We are reporting two cases of APS in SLE patients that presented with CRVO (case 1) and vaso-occlusive lupus retinopathy (case 2). Both cases were positive for antiphospholipid antibody (APA) and were treated with immunosuppression, anticoagulant, and laser treatment. Thus, screening for APA is vital in SLE patients with lupus retinopathy, as prompt treatment with anticoagulants is important to prevent further vascular thrombosis, which worsens the visual prognosis. Keywords: systemic lupus erythematosus, antiphospholipid antibody, central retinal vein occlusion, vaso-occlusive retinopathyHong-Kee NMei-Fong CAzhany YZunaina EDove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2014, Iss default, Pp 2359-2363 (2014)
institution	DOAJ
collection	DOAJ
language	EN
topic	Ophthalmology RE1-994
spellingShingle	Ophthalmology RE1-994 Hong-Kee N Mei-Fong C Azhany Y Zunaina E Antiphospholipid syndrome in lupus retinopathy
description	Ng Hong-Kee,1,2 Chong Mei-Fong,2 Yaakub Azhany,1 Embong Zunaina1 1Department of Ophthalmology, School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian, Kelantan, Malaysia; 2Department of Ophthalmology, Hospital Raja Permaisuri Bainun, Ipoh, Perak, Malaysia Abstract: Systemic lupus erythematosus (SLE) is a chronic, multisystem, autoimmune disease that can affect any part of the human body including the eyes. Common blinding ocular manifestations include central retinal artery occlusion (CRAO), central retinal vein occlusion (CRVO), severe vaso-occlusive retinopathy, and optic nerve involvement. Antiphospholipid syndrome (APS) in lupus is usually associated with large vessel occlusions and needs prompt treatment with anticoagulant. We are reporting two cases of APS in SLE patients that presented with CRVO (case 1) and vaso-occlusive lupus retinopathy (case 2). Both cases were positive for antiphospholipid antibody (APA) and were treated with immunosuppression, anticoagulant, and laser treatment. Thus, screening for APA is vital in SLE patients with lupus retinopathy, as prompt treatment with anticoagulants is important to prevent further vascular thrombosis, which worsens the visual prognosis. Keywords: systemic lupus erythematosus, antiphospholipid antibody, central retinal vein occlusion, vaso-occlusive retinopathy
format	article
author	Hong-Kee N Mei-Fong C Azhany Y Zunaina E
author_facet	Hong-Kee N Mei-Fong C Azhany Y Zunaina E
author_sort	Hong-Kee N
title	Antiphospholipid syndrome in lupus retinopathy
title_short	Antiphospholipid syndrome in lupus retinopathy
title_full	Antiphospholipid syndrome in lupus retinopathy
title_fullStr	Antiphospholipid syndrome in lupus retinopathy
title_full_unstemmed	Antiphospholipid syndrome in lupus retinopathy
title_sort	antiphospholipid syndrome in lupus retinopathy
publisher	Dove Medical Press
publishDate	2014
url	https://doaj.org/article/d89f6d618ebe4939b7ffaec61546e7b5
work_keys_str_mv	AT hongkeen antiphospholipidsyndromeinlupusretinopathy AT meifongc antiphospholipidsyndromeinlupusretinopathy AT azhanyy antiphospholipidsyndromeinlupusretinopathy AT zunainae antiphospholipidsyndromeinlupusretinopathy
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Antiphospholipid syndrome in lupus retinopathy

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