Multiple myeloma increases nerve growth factor and other pain-related markers through interactions with the bone microenvironment
Abstract Interactions between multiple myeloma (MM) and bone marrow (BM) are well documented to support tumour growth, yet the cellular mechanisms underlying pain in MM are poorly understood. We have used in vivo murine models of MM to show significant induction of nerve growth factor (NGF) by the t...
Guardado en:
Autores principales: | Sam W. Z. Olechnowicz, Megan M. Weivoda, Seint T. Lwin, Szi K. Leung, Sarah Gooding, Guido Nador, Muhammed Kassim Javaid, Karthik Ramasamy, Srinivasa R. Rao, James R. Edwards, Claire M. Edwards |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2019
|
Materias: | |
Acceso en línea: | https://doaj.org/article/d8afcd0e1a894dd9a3e3bba9c52aefc9 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Transcriptomic profiling of the myeloma bone-lining niche reveals BMP signalling inhibition to improve bone disease
por: Sarah Gooding, et al.
Publicado: (2019) -
Computational modeling of interactions between multiple myeloma and the bone microenvironment.
por: Yan Wang, et al.
Publicado: (2011) -
Tumor microenvironment-targeted nanoparticles loaded with bortezomib and ROCK inhibitor improve efficacy in multiple myeloma
por: Cinzia Federico, et al.
Publicado: (2020) -
Comprehensive Analysis of m6A RNA Methylation Regulators in the Prognosis and Immune Microenvironment of Multiple Myeloma
por: Rui Liu, et al.
Publicado: (2021) -
Microenvironment-responsive immunoregulatory electrospun fibers for promoting nerve function recovery
por: Kun Xi, et al.
Publicado: (2020)