Development of custom lead shield and strainer for targeted irradiation for mice in the gamma cell chamber

Abstract We presented a development of a custom lead shield and mouse strainer for targeted irradiation from the gamma-cell chamber. This study was divided into two parts i.e., to (i) fabricate the shield and strainer from a lead (Pb) and (ii) optimize the irradiation to the mice-bearing tumour mode...

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Autores principales:	Nurhaslina Hasan, Nur Fatihah Ronny Sham, Muhammad Khalis Abdul Karim, Syed Baharom Syed Ahmad Fuad, Narimah Abdul Hamid Hasani, Effat Omar, Mohammad Johari Ibahim
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/d8b27a3ac16045e485f79ca42c49abdb
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spelling	oai:doaj.org-article:d8b27a3ac16045e485f79ca42c49abdb2021-12-02T16:14:10ZDevelopment of custom lead shield and strainer for targeted irradiation for mice in the gamma cell chamber10.1038/s41598-021-93964-52045-2322https://doaj.org/article/d8b27a3ac16045e485f79ca42c49abdb2021-07-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-93964-5https://doaj.org/toc/2045-2322Abstract We presented a development of a custom lead shield and mouse strainer for targeted irradiation from the gamma-cell chamber. This study was divided into two parts i.e., to (i) fabricate the shield and strainer from a lead (Pb) and (ii) optimize the irradiation to the mice-bearing tumour model with 2 and 8 Gy absorbed doses. The lead shielding was fabricated into a cuboid shape with a canal on the top and a hole on the vertical side for the beam path. Respective deliveries doses of 28 and 75 Gy from gamma-cell were used to achieve 2 and 8 Gy absorbed doses at the tumour sites.Nurhaslina HasanNur Fatihah Ronny ShamMuhammad Khalis Abdul KarimSyed Baharom Syed Ahmad FuadNarimah Abdul Hamid HasaniEffat OmarMohammad Johari IbahimNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-7 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Nurhaslina Hasan Nur Fatihah Ronny Sham Muhammad Khalis Abdul Karim Syed Baharom Syed Ahmad Fuad Narimah Abdul Hamid Hasani Effat Omar Mohammad Johari Ibahim Development of custom lead shield and strainer for targeted irradiation for mice in the gamma cell chamber
description	Abstract We presented a development of a custom lead shield and mouse strainer for targeted irradiation from the gamma-cell chamber. This study was divided into two parts i.e., to (i) fabricate the shield and strainer from a lead (Pb) and (ii) optimize the irradiation to the mice-bearing tumour model with 2 and 8 Gy absorbed doses. The lead shielding was fabricated into a cuboid shape with a canal on the top and a hole on the vertical side for the beam path. Respective deliveries doses of 28 and 75 Gy from gamma-cell were used to achieve 2 and 8 Gy absorbed doses at the tumour sites.
format	article
author	Nurhaslina Hasan Nur Fatihah Ronny Sham Muhammad Khalis Abdul Karim Syed Baharom Syed Ahmad Fuad Narimah Abdul Hamid Hasani Effat Omar Mohammad Johari Ibahim
author_facet	Nurhaslina Hasan Nur Fatihah Ronny Sham Muhammad Khalis Abdul Karim Syed Baharom Syed Ahmad Fuad Narimah Abdul Hamid Hasani Effat Omar Mohammad Johari Ibahim
author_sort	Nurhaslina Hasan
title	Development of custom lead shield and strainer for targeted irradiation for mice in the gamma cell chamber
title_short	Development of custom lead shield and strainer for targeted irradiation for mice in the gamma cell chamber
title_full	Development of custom lead shield and strainer for targeted irradiation for mice in the gamma cell chamber
title_fullStr	Development of custom lead shield and strainer for targeted irradiation for mice in the gamma cell chamber
title_full_unstemmed	Development of custom lead shield and strainer for targeted irradiation for mice in the gamma cell chamber
title_sort	development of custom lead shield and strainer for targeted irradiation for mice in the gamma cell chamber
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/d8b27a3ac16045e485f79ca42c49abdb
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Development of custom lead shield and strainer for targeted irradiation for mice in the gamma cell chamber

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