The GTPase domain of gamma-tubulin is required for normal mitochondrial function and spatial organization
Lisa Lindström et al. find that the gamma-tubulin cellular network is required to maintain mitochondrial function and organization in the cell. Knockdown of gamma-tubulin or loss of its GTPase domain disrupts the mitochondrial network and alters respiratory capacity and expression of mitochondrial g...
Guardado en:
Autores principales: | , , , , , , , , , |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2018
|
Materias: | |
Acceso en línea: | https://doaj.org/article/d8b682b135e44aecbc719b783aa778cd |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
id |
oai:doaj.org-article:d8b682b135e44aecbc719b783aa778cd |
---|---|
record_format |
dspace |
spelling |
oai:doaj.org-article:d8b682b135e44aecbc719b783aa778cd2021-12-02T12:30:50ZThe GTPase domain of gamma-tubulin is required for normal mitochondrial function and spatial organization10.1038/s42003-018-0037-32399-3642https://doaj.org/article/d8b682b135e44aecbc719b783aa778cd2018-05-01T00:00:00Zhttps://doi.org/10.1038/s42003-018-0037-3https://doaj.org/toc/2399-3642Lisa Lindström et al. find that the gamma-tubulin cellular network is required to maintain mitochondrial function and organization in the cell. Knockdown of gamma-tubulin or loss of its GTPase domain disrupts the mitochondrial network and alters respiratory capacity and expression of mitochondrial genes.Lisa LindströmTongbin LiDarina MalychevaArun KancharlaHelén NilssonNeelanjan VishnuHindrik MulderMartin JohanssonCatalina Ana RossellóMaria Alvarado-KristenssonNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 1, Iss 1, Pp 1-18 (2018) |
institution |
DOAJ |
collection |
DOAJ |
language |
EN |
topic |
Biology (General) QH301-705.5 |
spellingShingle |
Biology (General) QH301-705.5 Lisa Lindström Tongbin Li Darina Malycheva Arun Kancharla Helén Nilsson Neelanjan Vishnu Hindrik Mulder Martin Johansson Catalina Ana Rosselló Maria Alvarado-Kristensson The GTPase domain of gamma-tubulin is required for normal mitochondrial function and spatial organization |
description |
Lisa Lindström et al. find that the gamma-tubulin cellular network is required to maintain mitochondrial function and organization in the cell. Knockdown of gamma-tubulin or loss of its GTPase domain disrupts the mitochondrial network and alters respiratory capacity and expression of mitochondrial genes. |
format |
article |
author |
Lisa Lindström Tongbin Li Darina Malycheva Arun Kancharla Helén Nilsson Neelanjan Vishnu Hindrik Mulder Martin Johansson Catalina Ana Rosselló Maria Alvarado-Kristensson |
author_facet |
Lisa Lindström Tongbin Li Darina Malycheva Arun Kancharla Helén Nilsson Neelanjan Vishnu Hindrik Mulder Martin Johansson Catalina Ana Rosselló Maria Alvarado-Kristensson |
author_sort |
Lisa Lindström |
title |
The GTPase domain of gamma-tubulin is required for normal mitochondrial function and spatial organization |
title_short |
The GTPase domain of gamma-tubulin is required for normal mitochondrial function and spatial organization |
title_full |
The GTPase domain of gamma-tubulin is required for normal mitochondrial function and spatial organization |
title_fullStr |
The GTPase domain of gamma-tubulin is required for normal mitochondrial function and spatial organization |
title_full_unstemmed |
The GTPase domain of gamma-tubulin is required for normal mitochondrial function and spatial organization |
title_sort |
gtpase domain of gamma-tubulin is required for normal mitochondrial function and spatial organization |
publisher |
Nature Portfolio |
publishDate |
2018 |
url |
https://doaj.org/article/d8b682b135e44aecbc719b783aa778cd |
work_keys_str_mv |
AT lisalindstrom thegtpasedomainofgammatubulinisrequiredfornormalmitochondrialfunctionandspatialorganization AT tongbinli thegtpasedomainofgammatubulinisrequiredfornormalmitochondrialfunctionandspatialorganization AT darinamalycheva thegtpasedomainofgammatubulinisrequiredfornormalmitochondrialfunctionandspatialorganization AT arunkancharla thegtpasedomainofgammatubulinisrequiredfornormalmitochondrialfunctionandspatialorganization AT helennilsson thegtpasedomainofgammatubulinisrequiredfornormalmitochondrialfunctionandspatialorganization AT neelanjanvishnu thegtpasedomainofgammatubulinisrequiredfornormalmitochondrialfunctionandspatialorganization AT hindrikmulder thegtpasedomainofgammatubulinisrequiredfornormalmitochondrialfunctionandspatialorganization AT martinjohansson thegtpasedomainofgammatubulinisrequiredfornormalmitochondrialfunctionandspatialorganization AT catalinaanarossello thegtpasedomainofgammatubulinisrequiredfornormalmitochondrialfunctionandspatialorganization AT mariaalvaradokristensson thegtpasedomainofgammatubulinisrequiredfornormalmitochondrialfunctionandspatialorganization AT lisalindstrom gtpasedomainofgammatubulinisrequiredfornormalmitochondrialfunctionandspatialorganization AT tongbinli gtpasedomainofgammatubulinisrequiredfornormalmitochondrialfunctionandspatialorganization AT darinamalycheva gtpasedomainofgammatubulinisrequiredfornormalmitochondrialfunctionandspatialorganization AT arunkancharla gtpasedomainofgammatubulinisrequiredfornormalmitochondrialfunctionandspatialorganization AT helennilsson gtpasedomainofgammatubulinisrequiredfornormalmitochondrialfunctionandspatialorganization AT neelanjanvishnu gtpasedomainofgammatubulinisrequiredfornormalmitochondrialfunctionandspatialorganization AT hindrikmulder gtpasedomainofgammatubulinisrequiredfornormalmitochondrialfunctionandspatialorganization AT martinjohansson gtpasedomainofgammatubulinisrequiredfornormalmitochondrialfunctionandspatialorganization AT catalinaanarossello gtpasedomainofgammatubulinisrequiredfornormalmitochondrialfunctionandspatialorganization AT mariaalvaradokristensson gtpasedomainofgammatubulinisrequiredfornormalmitochondrialfunctionandspatialorganization |
_version_ |
1718394364879699968 |