Assessment of Suprachoroidal Injection of Triamcinolone Acetonide in Cases of Diabetic Macular Edema

Background: Diabetic retinopathy [DR] remains one of the main causes of visual reduction in the world. The visual reduction in patients with DR is usually due to diabetic macular edema [DME].Suprachoroidal triamcinolone acetonide injection is a new effective modality used for the management of diabe...

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Autores principales:	Mahmoud Samy Yousef, Yonis Abd Elhafez, Mohamed Farag
Formato:	article
Lenguaje:	EN
Publicado:	Al-Azhar University, Faculty of Medicine (Damietta) 2021
Materias:	keywords: diabetic macular edema triamcinolone acetonide suprachoroidal space optical coherence tomography Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/d8ba62128e7a426cbe73606d8c649936
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spelling	oai:doaj.org-article:d8ba62128e7a426cbe73606d8c6499362021-12-02T14:44:39ZAssessment of Suprachoroidal Injection of Triamcinolone Acetonide in Cases of Diabetic Macular Edema2636-41742682-378010.21608/ijma.2021.55079.1230https://doaj.org/article/d8ba62128e7a426cbe73606d8c6499362021-04-01T00:00:00Zhttps://ijma.journals.ekb.eg/article_158325_91c5954600b6d82bc8ff3ba4e0eab677.pdfhttps://doaj.org/toc/2636-4174https://doaj.org/toc/2682-3780Background: Diabetic retinopathy [DR] remains one of the main causes of visual reduction in the world. The visual reduction in patients with DR is usually due to diabetic macular edema [DME].Suprachoroidal triamcinolone acetonide injection is a new effective modality used for the management of diabetic macular edema. The aim of the work: To assess the visual acuity [VA], central macular thickness [CMT] by optical coherence tomography [OCT] and intraocular pressure [IOP] measurement in patients with DME injected with Triamcinolone Acetonide through suprachoroidal space. Patients and Methods: Forty eyes of 37 patients [18 males and 19 females]] with DME were included and followed-up for 6 months to assess VA, CMT and IOP. Patients were included if they were diagnosed as DME. Results: Baseline measurements were logMAR best corrected visual acuity [VA] which was 0.83 ± 0.09, [OCT] which was 422.42 ± 64.1 µm and [IOP] which was 15.25 ± 1.46 mmHg. Post injection measurements of VA during the four points of the follow-up period showed statistically significant improvement. At one-week post-injection, logMAR VA was 0.82 ± 0.09, at one-month follow-up was 0.72 ± 0.09, at three months was 0.68 ± 0.1, at six months, was 0.62 ± 0.1,. OCT follow-up measurements showed highly significant improvements, which started from the first week post-injection till the end of the follow-up period at six months point. At one week, it measured 391.7 ± 60.6 µm, at one month the measurement was 337.1 ± 54.5 µm, at three months was 302.7 ± 46.5, at six months, was 267.9 ± 40.7. Conclusion: Injection of TA to the suprachoroidal space in DME, was well tolerated without any serious ocular adverse events and produced significant resolution in CST and significant improvement in BCVA.Mahmoud Samy YousefYonis Abd ElhafezMohamed FaragAl-Azhar University, Faculty of Medicine (Damietta)articlekeywords: diabeticmacular edematriamcinolone acetonidesuprachoroidal spaceoptical coherence tomographyMedicine (General)R5-920ENInternational Journal of Medical Arts, Vol 3, Iss 2, Pp 1384-1389 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	keywords: diabetic macular edema triamcinolone acetonide suprachoroidal space optical coherence tomography Medicine (General) R5-920
spellingShingle	keywords: diabetic macular edema triamcinolone acetonide suprachoroidal space optical coherence tomography Medicine (General) R5-920 Mahmoud Samy Yousef Yonis Abd Elhafez Mohamed Farag Assessment of Suprachoroidal Injection of Triamcinolone Acetonide in Cases of Diabetic Macular Edema
description	Background: Diabetic retinopathy [DR] remains one of the main causes of visual reduction in the world. The visual reduction in patients with DR is usually due to diabetic macular edema [DME].Suprachoroidal triamcinolone acetonide injection is a new effective modality used for the management of diabetic macular edema. The aim of the work: To assess the visual acuity [VA], central macular thickness [CMT] by optical coherence tomography [OCT] and intraocular pressure [IOP] measurement in patients with DME injected with Triamcinolone Acetonide through suprachoroidal space. Patients and Methods: Forty eyes of 37 patients [18 males and 19 females]] with DME were included and followed-up for 6 months to assess VA, CMT and IOP. Patients were included if they were diagnosed as DME. Results: Baseline measurements were logMAR best corrected visual acuity [VA] which was 0.83 ± 0.09, [OCT] which was 422.42 ± 64.1 µm and [IOP] which was 15.25 ± 1.46 mmHg. Post injection measurements of VA during the four points of the follow-up period showed statistically significant improvement. At one-week post-injection, logMAR VA was 0.82 ± 0.09, at one-month follow-up was 0.72 ± 0.09, at three months was 0.68 ± 0.1, at six months, was 0.62 ± 0.1,. OCT follow-up measurements showed highly significant improvements, which started from the first week post-injection till the end of the follow-up period at six months point. At one week, it measured 391.7 ± 60.6 µm, at one month the measurement was 337.1 ± 54.5 µm, at three months was 302.7 ± 46.5, at six months, was 267.9 ± 40.7. Conclusion: Injection of TA to the suprachoroidal space in DME, was well tolerated without any serious ocular adverse events and produced significant resolution in CST and significant improvement in BCVA.
format	article
author	Mahmoud Samy Yousef Yonis Abd Elhafez Mohamed Farag
author_facet	Mahmoud Samy Yousef Yonis Abd Elhafez Mohamed Farag
author_sort	Mahmoud Samy Yousef
title	Assessment of Suprachoroidal Injection of Triamcinolone Acetonide in Cases of Diabetic Macular Edema
title_short	Assessment of Suprachoroidal Injection of Triamcinolone Acetonide in Cases of Diabetic Macular Edema
title_full	Assessment of Suprachoroidal Injection of Triamcinolone Acetonide in Cases of Diabetic Macular Edema
title_fullStr	Assessment of Suprachoroidal Injection of Triamcinolone Acetonide in Cases of Diabetic Macular Edema
title_full_unstemmed	Assessment of Suprachoroidal Injection of Triamcinolone Acetonide in Cases of Diabetic Macular Edema
title_sort	assessment of suprachoroidal injection of triamcinolone acetonide in cases of diabetic macular edema
publisher	Al-Azhar University, Faculty of Medicine (Damietta)
publishDate	2021
url	https://doaj.org/article/d8ba62128e7a426cbe73606d8c649936
work_keys_str_mv	AT mahmoudsamyyousef assessmentofsuprachoroidalinjectionoftriamcinoloneacetonideincasesofdiabeticmacularedema AT yonisabdelhafez assessmentofsuprachoroidalinjectionoftriamcinoloneacetonideincasesofdiabeticmacularedema AT mohamedfarag assessmentofsuprachoroidalinjectionoftriamcinoloneacetonideincasesofdiabeticmacularedema
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Assessment of Suprachoroidal Injection of Triamcinolone Acetonide in Cases of Diabetic Macular Edema

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