Mesenchymal stromal cells mitigate liver damage after extended resection in the pig by modulating thrombospondin-1/TGF-β

Mesenchymal stromal cells mitigate liver damage after extended resection in the pig by modulating thrombospondin-1/TGF-β

Abstract Post-surgery liver failure is a serious complication for patients after extended partial hepatectomies (ePHx). Previously, we demonstrated in the pig model that transplantation of mesenchymal stromal cells (MSC) improved circulatory maintenance and supported multi-organ functions after 70%...

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Autores principales: Sandra Nickel, Sebastian Vlaic, Madlen Christ, Kristin Schubert, Reinhard Henschler, Franziska Tautenhahn, Caroline Burger, Hagen Kühne, Silvio Erler, Andreas Roth, Christiane Wild, Janine Brach, Seddik Hammad, Claudia Gittel, Manja Baunack, Undine Lange, Johannes Broschewitz, Peggy Stock, Isabella Metelmann, Michael Bartels, Uta-Carolin Pietsch, Sebastian Krämer, Uwe Eichfeld, Martin von Bergen, Steven Dooley, Hans-Michael Tautenhahn, Bruno Christ
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Medicine
R
Acceso en línea:https://doaj.org/article/d8c5dc1a3f2a4ecc8f2999b0b4e1c185
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