The ever-changing landscape in modern dentistry therapeutics – Enhancing the emptying quiver of the periodontist

Introduction/Objectives: Periodontitis comprises of a wide range of inflammatory conditions of the gums leading to soft tissue damage and attachment loss. The initiation of periodontitis constitutes a rather complex disease pathogenesis which is based on pathogenic shifts of the oral microbiota comb...

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Autores principales:	Dimitra Diakoumopoulou, Maria Magana, Ioannis K. Karoussis, Chrysoula Nikolaou, Stylianos Chatzipanagiotou, Anastasios Ioannidis
Formato:	article
Lenguaje:	EN
Publicado:	Elsevier 2021
Materias:	Periodontitis Oral microbiome Biofilm Therapeutics Curcumin Photodynamic therapy Science (General) Q1-390 Social sciences (General) H1-99
Acceso en línea:	https://doaj.org/article/d8c74bcce23e4bc39d4b8da130c871bf
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spelling	oai:doaj.org-article:d8c74bcce23e4bc39d4b8da130c871bf2021-12-02T05:02:45ZThe ever-changing landscape in modern dentistry therapeutics – Enhancing the emptying quiver of the periodontist2405-844010.1016/j.heliyon.2021.e08342https://doaj.org/article/d8c74bcce23e4bc39d4b8da130c871bf2021-11-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S2405844021024452https://doaj.org/toc/2405-8440Introduction/Objectives: Periodontitis comprises of a wide range of inflammatory conditions of the gums leading to soft tissue damage and attachment loss. The initiation of periodontitis constitutes a rather complex disease pathogenesis which is based on pathogenic shifts of the oral microbiota combined with the host-microbiome interactions. The severity of the periodontitis is multifactorial depending on genetic, environmental, as well as host immunity factors. Data and sources: To make an inclusive analysis on the periodontitis therapeutics, reading of the recent relevant literature was carried out using the MEDLINE/PubMed database, Google Scholar and the NIH public online database for clinical trials (http://www.clinicaltrials.gov). Conclusions: Tackling the inflammation associated periodontal defects can be succeeded with conventional therapy or resective and regenerative treatment. To date, the mechanical removal of the supragingival and subgingival biofilm is considered the “gold standard” of periodontal therapy in combination with the use of antibacterial compounds. The antimicrobial resistance phenomenon tends to turn all the currently applied antibacterials into “endangered species”. Ongoing efforts through the conduct of clinical trials should be focused on understanding the advantages of modern approaches in comparison to traditional therapies.Dimitra DiakoumopoulouMaria MaganaIoannis K. KaroussisChrysoula NikolaouStylianos ChatzipanagiotouAnastasios IoannidisElsevierarticlePeriodontitisOral microbiomeBiofilmTherapeuticsCurcuminPhotodynamic therapyScience (General)Q1-390Social sciences (General)H1-99ENHeliyon, Vol 7, Iss 11, Pp e08342- (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Periodontitis Oral microbiome Biofilm Therapeutics Curcumin Photodynamic therapy Science (General) Q1-390 Social sciences (General) H1-99
spellingShingle	Periodontitis Oral microbiome Biofilm Therapeutics Curcumin Photodynamic therapy Science (General) Q1-390 Social sciences (General) H1-99 Dimitra Diakoumopoulou Maria Magana Ioannis K. Karoussis Chrysoula Nikolaou Stylianos Chatzipanagiotou Anastasios Ioannidis The ever-changing landscape in modern dentistry therapeutics – Enhancing the emptying quiver of the periodontist
description	Introduction/Objectives: Periodontitis comprises of a wide range of inflammatory conditions of the gums leading to soft tissue damage and attachment loss. The initiation of periodontitis constitutes a rather complex disease pathogenesis which is based on pathogenic shifts of the oral microbiota combined with the host-microbiome interactions. The severity of the periodontitis is multifactorial depending on genetic, environmental, as well as host immunity factors. Data and sources: To make an inclusive analysis on the periodontitis therapeutics, reading of the recent relevant literature was carried out using the MEDLINE/PubMed database, Google Scholar and the NIH public online database for clinical trials (http://www.clinicaltrials.gov). Conclusions: Tackling the inflammation associated periodontal defects can be succeeded with conventional therapy or resective and regenerative treatment. To date, the mechanical removal of the supragingival and subgingival biofilm is considered the “gold standard” of periodontal therapy in combination with the use of antibacterial compounds. The antimicrobial resistance phenomenon tends to turn all the currently applied antibacterials into “endangered species”. Ongoing efforts through the conduct of clinical trials should be focused on understanding the advantages of modern approaches in comparison to traditional therapies.
format	article
author	Dimitra Diakoumopoulou Maria Magana Ioannis K. Karoussis Chrysoula Nikolaou Stylianos Chatzipanagiotou Anastasios Ioannidis
author_facet	Dimitra Diakoumopoulou Maria Magana Ioannis K. Karoussis Chrysoula Nikolaou Stylianos Chatzipanagiotou Anastasios Ioannidis
author_sort	Dimitra Diakoumopoulou
title	The ever-changing landscape in modern dentistry therapeutics – Enhancing the emptying quiver of the periodontist
title_short	The ever-changing landscape in modern dentistry therapeutics – Enhancing the emptying quiver of the periodontist
title_full	The ever-changing landscape in modern dentistry therapeutics – Enhancing the emptying quiver of the periodontist
title_fullStr	The ever-changing landscape in modern dentistry therapeutics – Enhancing the emptying quiver of the periodontist
title_full_unstemmed	The ever-changing landscape in modern dentistry therapeutics – Enhancing the emptying quiver of the periodontist
title_sort	ever-changing landscape in modern dentistry therapeutics – enhancing the emptying quiver of the periodontist
publisher	Elsevier
publishDate	2021
url	https://doaj.org/article/d8c74bcce23e4bc39d4b8da130c871bf
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The ever-changing landscape in modern dentistry therapeutics – Enhancing the emptying quiver of the periodontist

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