Structure of the membrane anchor of pestivirus glycoprotein E(rns), a long tilted amphipathic helix.

E(rns) is an essential virion glycoprotein with RNase activity that suppresses host cellular innate immune responses upon being partially secreted from the infected cells. Its unusual C-terminus plays multiple roles, as the amphiphilic helix acts as a membrane anchor, as a signal peptidase cleavage...

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Autores principales: Daniel Aberle, Claudia Muhle-Goll, Jochen Bürck, Moritz Wolf, Sabine Reißer, Burkhard Luy, Wolfgang Wenzel, Anne S Ulrich, Gregor Meyers
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2014
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Acceso en línea:https://doaj.org/article/d8c7c5b4135d46a0b110c9e0d75db212
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