Distinct homeostatic modulations stabilize reduced postsynaptic receptivity in response to presynaptic DLK signaling

Dual leucine zipper kinase (DLK) activates an intrinsic neuronal response to injury and is also implicated in neurodegeneration. Here, Goel and Dickman characterize how postsynaptic targets adapt to presynaptic DLK signaling through a downregulation of synaptic strength.

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Detalles Bibliográficos
Autores principales:	Pragya Goel, Dion Dickman
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/d8d3fb345bee4339bc6dc9b4dda7bb60
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spelling	oai:doaj.org-article:d8d3fb345bee4339bc6dc9b4dda7bb602021-12-02T14:40:04ZDistinct homeostatic modulations stabilize reduced postsynaptic receptivity in response to presynaptic DLK signaling10.1038/s41467-018-04270-02041-1723https://doaj.org/article/d8d3fb345bee4339bc6dc9b4dda7bb602018-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-04270-0https://doaj.org/toc/2041-1723Dual leucine zipper kinase (DLK) activates an intrinsic neuronal response to injury and is also implicated in neurodegeneration. Here, Goel and Dickman characterize how postsynaptic targets adapt to presynaptic DLK signaling through a downregulation of synaptic strength.Pragya GoelDion DickmanNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Pragya Goel Dion Dickman Distinct homeostatic modulations stabilize reduced postsynaptic receptivity in response to presynaptic DLK signaling
description	Dual leucine zipper kinase (DLK) activates an intrinsic neuronal response to injury and is also implicated in neurodegeneration. Here, Goel and Dickman characterize how postsynaptic targets adapt to presynaptic DLK signaling through a downregulation of synaptic strength.
format	article
author	Pragya Goel Dion Dickman
author_facet	Pragya Goel Dion Dickman
author_sort	Pragya Goel
title	Distinct homeostatic modulations stabilize reduced postsynaptic receptivity in response to presynaptic DLK signaling
title_short	Distinct homeostatic modulations stabilize reduced postsynaptic receptivity in response to presynaptic DLK signaling
title_full	Distinct homeostatic modulations stabilize reduced postsynaptic receptivity in response to presynaptic DLK signaling
title_fullStr	Distinct homeostatic modulations stabilize reduced postsynaptic receptivity in response to presynaptic DLK signaling
title_full_unstemmed	Distinct homeostatic modulations stabilize reduced postsynaptic receptivity in response to presynaptic DLK signaling
title_sort	distinct homeostatic modulations stabilize reduced postsynaptic receptivity in response to presynaptic dlk signaling
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/d8d3fb345bee4339bc6dc9b4dda7bb60
work_keys_str_mv	AT pragyagoel distincthomeostaticmodulationsstabilizereducedpostsynapticreceptivityinresponsetopresynapticdlksignaling AT diondickman distincthomeostaticmodulationsstabilizereducedpostsynapticreceptivityinresponsetopresynapticdlksignaling
_version_	1718390446442414080

Distinct homeostatic modulations stabilize reduced postsynaptic receptivity in response to presynaptic DLK signaling

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