αvβ3 Integrin induces partial EMT independent of TGF-β signaling

Kariya, Oyama et al. propose that αvβ3 can drive a partial EMT phenotype characterized by maintained E-cadherin expression and upregulation of mesenchymal markers. This hybrid EMT state is independent of TGF-β1 signaling and characterised by increased migration, invasion, tumor cell proliferation, s...

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Autores principales:	Yoshinobu Kariya, Midori Oyama, Takato Suzuki, Yukiko Kariya
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/d8dded810a1f4dd2ba943cbec8b2bb05
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spelling	oai:doaj.org-article:d8dded810a1f4dd2ba943cbec8b2bb052021-12-02T17:32:55Zαvβ3 Integrin induces partial EMT independent of TGF-β signaling10.1038/s42003-021-02003-62399-3642https://doaj.org/article/d8dded810a1f4dd2ba943cbec8b2bb052021-04-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-02003-6https://doaj.org/toc/2399-3642Kariya, Oyama et al. propose that αvβ3 can drive a partial EMT phenotype characterized by maintained E-cadherin expression and upregulation of mesenchymal markers. This hybrid EMT state is independent of TGF-β1 signaling and characterised by increased migration, invasion, tumor cell proliferation, stemness and metastatic capacity.Yoshinobu KariyaMidori OyamaTakato SuzukiYukiko KariyaNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-11 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Biology (General) QH301-705.5
spellingShingle	Biology (General) QH301-705.5 Yoshinobu Kariya Midori Oyama Takato Suzuki Yukiko Kariya αvβ3 Integrin induces partial EMT independent of TGF-β signaling
description	Kariya, Oyama et al. propose that αvβ3 can drive a partial EMT phenotype characterized by maintained E-cadherin expression and upregulation of mesenchymal markers. This hybrid EMT state is independent of TGF-β1 signaling and characterised by increased migration, invasion, tumor cell proliferation, stemness and metastatic capacity.
format	article
author	Yoshinobu Kariya Midori Oyama Takato Suzuki Yukiko Kariya
author_facet	Yoshinobu Kariya Midori Oyama Takato Suzuki Yukiko Kariya
author_sort	Yoshinobu Kariya
title	αvβ3 Integrin induces partial EMT independent of TGF-β signaling
title_short	αvβ3 Integrin induces partial EMT independent of TGF-β signaling
title_full	αvβ3 Integrin induces partial EMT independent of TGF-β signaling
title_fullStr	αvβ3 Integrin induces partial EMT independent of TGF-β signaling
title_full_unstemmed	αvβ3 Integrin induces partial EMT independent of TGF-β signaling
title_sort	αvβ3 integrin induces partial emt independent of tgf-β signaling
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/d8dded810a1f4dd2ba943cbec8b2bb05
work_keys_str_mv	AT yoshinobukariya avb3integrininducespartialemtindependentoftgfbsignaling AT midorioyama avb3integrininducespartialemtindependentoftgfbsignaling AT takatosuzuki avb3integrininducespartialemtindependentoftgfbsignaling AT yukikokariya avb3integrininducespartialemtindependentoftgfbsignaling
_version_	1718380152979718144

αvβ3 Integrin induces partial EMT independent of TGF-β signaling

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