αvβ3 Integrin induces partial EMT independent of TGF-β signaling

Kariya, Oyama et al. propose that αvβ3 can drive a partial EMT phenotype characterized by maintained E-cadherin expression and upregulation of mesenchymal markers. This hybrid EMT state is independent of TGF-β1 signaling and characterised by increased migration, invasion, tumor cell proliferation, s...

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Autores principales: Yoshinobu Kariya, Midori Oyama, Takato Suzuki, Yukiko Kariya
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/d8dded810a1f4dd2ba943cbec8b2bb05
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