Dynamics of molecular evolution and phylogeography of Barley yellow dwarf virus-PAV.

Barley yellow dwarf virus (BYDV) species PAV occurs frequently in irrigated wheat fields worldwide and can be efficiently transmitted by aphids. Isolates of BYDV-PAV from different countries show great divergence both in genomic sequences and pathogenicity. Despite its economical importance, the gen...

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Autores principales:	Beilei Wu, Alexandra Blanchard-Letort, Yan Liu, Guanghe Zhou, Xifeng Wang, Santiago F Elena
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2011
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/d8e2c50add2b450a9099becdbafb296b
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spelling	oai:doaj.org-article:d8e2c50add2b450a9099becdbafb296b2021-11-18T06:59:12ZDynamics of molecular evolution and phylogeography of Barley yellow dwarf virus-PAV.1932-620310.1371/journal.pone.0016896https://doaj.org/article/d8e2c50add2b450a9099becdbafb296b2011-02-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21326861/pdf/?tool=EBIhttps://doaj.org/toc/1932-6203Barley yellow dwarf virus (BYDV) species PAV occurs frequently in irrigated wheat fields worldwide and can be efficiently transmitted by aphids. Isolates of BYDV-PAV from different countries show great divergence both in genomic sequences and pathogenicity. Despite its economical importance, the genetic structure of natural BYDV-PAV populations, as well as of the mechanisms maintaining its high diversity, remain poorly explored. In this study, we investigate the dynamics of BYDV-PAV genome evolution utilizing time-structured data sets of complete genomic sequences from 58 isolates from different hosts obtained worldwide. First, we observed that BYDV-PAV exhibits a high frequency of homologous recombination. Second, our analysis revealed that BYDV-PAV genome evolves under purifying selection and at a substitution rate similar to other RNA viruses (3.158×10(-4) nucleotide substitutions/site/year). Phylogeography analyses show that the diversification of BYDV-PAV can be explained by local geographic adaptation as well as by host-driven adaptation. These results increase our understanding of the diversity, molecular evolutionary characteristics and epidemiological properties of an economically important plant RNA virus.Beilei WuAlexandra Blanchard-LetortYan LiuGuanghe ZhouXifeng WangSantiago F ElenaPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 6, Iss 2, p e16896 (2011)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Beilei Wu Alexandra Blanchard-Letort Yan Liu Guanghe Zhou Xifeng Wang Santiago F Elena Dynamics of molecular evolution and phylogeography of Barley yellow dwarf virus-PAV.
description	Barley yellow dwarf virus (BYDV) species PAV occurs frequently in irrigated wheat fields worldwide and can be efficiently transmitted by aphids. Isolates of BYDV-PAV from different countries show great divergence both in genomic sequences and pathogenicity. Despite its economical importance, the genetic structure of natural BYDV-PAV populations, as well as of the mechanisms maintaining its high diversity, remain poorly explored. In this study, we investigate the dynamics of BYDV-PAV genome evolution utilizing time-structured data sets of complete genomic sequences from 58 isolates from different hosts obtained worldwide. First, we observed that BYDV-PAV exhibits a high frequency of homologous recombination. Second, our analysis revealed that BYDV-PAV genome evolves under purifying selection and at a substitution rate similar to other RNA viruses (3.158×10(-4) nucleotide substitutions/site/year). Phylogeography analyses show that the diversification of BYDV-PAV can be explained by local geographic adaptation as well as by host-driven adaptation. These results increase our understanding of the diversity, molecular evolutionary characteristics and epidemiological properties of an economically important plant RNA virus.
format	article
author	Beilei Wu Alexandra Blanchard-Letort Yan Liu Guanghe Zhou Xifeng Wang Santiago F Elena
author_facet	Beilei Wu Alexandra Blanchard-Letort Yan Liu Guanghe Zhou Xifeng Wang Santiago F Elena
author_sort	Beilei Wu
title	Dynamics of molecular evolution and phylogeography of Barley yellow dwarf virus-PAV.
title_short	Dynamics of molecular evolution and phylogeography of Barley yellow dwarf virus-PAV.
title_full	Dynamics of molecular evolution and phylogeography of Barley yellow dwarf virus-PAV.
title_fullStr	Dynamics of molecular evolution and phylogeography of Barley yellow dwarf virus-PAV.
title_full_unstemmed	Dynamics of molecular evolution and phylogeography of Barley yellow dwarf virus-PAV.
title_sort	dynamics of molecular evolution and phylogeography of barley yellow dwarf virus-pav.
publisher	Public Library of Science (PLoS)
publishDate	2011
url	https://doaj.org/article/d8e2c50add2b450a9099becdbafb296b
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Dynamics of molecular evolution and phylogeography of Barley yellow dwarf virus-PAV.

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