Chaperone mediated detection of small molecule target binding in cells

Quantitative profiling of small molecule-protein binding in cells can aid basic biochemical research and drug discovery. Here, the authors develop the Heat Shock Protein Inhibition Protein Stability Assay (HIPStA) as a high-throughput method to assess cellular target engagement and identify new drug...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Kelvin F. Cho, Taylur P. Ma, Christopher M. Rose, Donald S. Kirkpatrick, Kebing Yu, Robert A. Blake
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
Materias:
Q
Acceso en línea:https://doaj.org/article/d8e4230757ef4fa5aa0391581b106a4b
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares