S100A9 extends lifespan in insulin deficiency

Insulin replacement is a valuable therapy for insulin deficiency, however, other therapies are being investigated to restore metabolic homeostasis. Here, the authors identify S100A9 as a leptin induced circulating cue that improves glucose and lipid homeostasis and extends survival in insulin defici...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Giorgio Ramadori, Sanda Ljubicic, Serena Ricci, Despoina Mikropoulou, Xavier Brenachot, Christelle Veyrat-Durebex, Ebru Aras, Rafael M. Ioris, Jordi Altirriba, Elisabeth Malle, Dirk Foell, Thomas Vogl, Roberto Coppari
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/d8ef89e1a35d49b49dd4c3ecbbce6524
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:d8ef89e1a35d49b49dd4c3ecbbce6524
record_format	dspace
spelling	oai:doaj.org-article:d8ef89e1a35d49b49dd4c3ecbbce65242021-12-02T15:36:05ZS100A9 extends lifespan in insulin deficiency10.1038/s41467-019-11498-x2041-1723https://doaj.org/article/d8ef89e1a35d49b49dd4c3ecbbce65242019-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-11498-xhttps://doaj.org/toc/2041-1723Insulin replacement is a valuable therapy for insulin deficiency, however, other therapies are being investigated to restore metabolic homeostasis. Here, the authors identify S100A9 as a leptin induced circulating cue that improves glucose and lipid homeostasis and extends survival in insulin deficient mice.Giorgio RamadoriSanda LjubicicSerena RicciDespoina MikropoulouXavier BrenachotChristelle Veyrat-DurebexEbru ArasRafael M. IorisJordi AltirribaElisabeth MalleDirk FoellThomas VoglRoberto CoppariNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Giorgio Ramadori Sanda Ljubicic Serena Ricci Despoina Mikropoulou Xavier Brenachot Christelle Veyrat-Durebex Ebru Aras Rafael M. Ioris Jordi Altirriba Elisabeth Malle Dirk Foell Thomas Vogl Roberto Coppari S100A9 extends lifespan in insulin deficiency
description	Insulin replacement is a valuable therapy for insulin deficiency, however, other therapies are being investigated to restore metabolic homeostasis. Here, the authors identify S100A9 as a leptin induced circulating cue that improves glucose and lipid homeostasis and extends survival in insulin deficient mice.
format	article
author	Giorgio Ramadori Sanda Ljubicic Serena Ricci Despoina Mikropoulou Xavier Brenachot Christelle Veyrat-Durebex Ebru Aras Rafael M. Ioris Jordi Altirriba Elisabeth Malle Dirk Foell Thomas Vogl Roberto Coppari
author_facet	Giorgio Ramadori Sanda Ljubicic Serena Ricci Despoina Mikropoulou Xavier Brenachot Christelle Veyrat-Durebex Ebru Aras Rafael M. Ioris Jordi Altirriba Elisabeth Malle Dirk Foell Thomas Vogl Roberto Coppari
author_sort	Giorgio Ramadori
title	S100A9 extends lifespan in insulin deficiency
title_short	S100A9 extends lifespan in insulin deficiency
title_full	S100A9 extends lifespan in insulin deficiency
title_fullStr	S100A9 extends lifespan in insulin deficiency
title_full_unstemmed	S100A9 extends lifespan in insulin deficiency
title_sort	s100a9 extends lifespan in insulin deficiency
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/d8ef89e1a35d49b49dd4c3ecbbce6524
work_keys_str_mv	AT giorgioramadori s100a9extendslifespanininsulindeficiency AT sandaljubicic s100a9extendslifespanininsulindeficiency AT serenaricci s100a9extendslifespanininsulindeficiency AT despoinamikropoulou s100a9extendslifespanininsulindeficiency AT xavierbrenachot s100a9extendslifespanininsulindeficiency AT christelleveyratdurebex s100a9extendslifespanininsulindeficiency AT ebruaras s100a9extendslifespanininsulindeficiency AT rafaelmioris s100a9extendslifespanininsulindeficiency AT jordialtirriba s100a9extendslifespanininsulindeficiency AT elisabethmalle s100a9extendslifespanininsulindeficiency AT dirkfoell s100a9extendslifespanininsulindeficiency AT thomasvogl s100a9extendslifespanininsulindeficiency AT robertocoppari s100a9extendslifespanininsulindeficiency
_version_	1718386385678761984

S100A9 extends lifespan in insulin deficiency

Ejemplares similares