Characterization of the Efflux Capability and Substrate Specificity of <named-content content-type="genus-species">Aspergillus fumigatus</named-content> PDR5-like ABC Transporters Expressed in <named-content content-type="genus-species">Saccharomyces cerevisiae</named-content>

Characterization of the Efflux Capability and Substrate Specificity of <named-content content-type="genus-species">Aspergillus fumigatus</named-content> PDR5-like ABC Transporters Expressed in <named-content content-type="genus-species">Saccharomyces cerevisiae</named-content>

ABSTRACT This research analyzed six Aspergillus fumigatus genes encoding putative efflux proteins for their roles as transporters. The A. fumigatus genes abcA, abcC, abcF, abcG, abcH, and abcI were cloned into plasmids and overexpressed in a Saccharomyces cerevisiae strain in which the highly active...

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Bibliographic Details
Main Authors: Brooke D. Esquivel, Jeffrey M. Rybak, Katherine S. Barker, Jarrod R. Fortwendel, P. David Rogers, Theodore C. White
Format: article
Language:EN
Published: American Society for Microbiology 2020
Subjects:
Aspergillus fumigatus
efflux
drug resistance
filamentous fungi
ABC transporter
PDR5
Microbiology
QR1-502
Online Access:https://doaj.org/article/d8fc063efb164397b16c0f643c17c6f3
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