In vitro self-replication and multicistronic expression of large synthetic genomes
A main objective of synthetic biology is the creation of chemical systems capable of replication and evolution. Here, the authors demonstrate combined self-replication and expression of multipartite genomes in vitro.
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Nature Portfolio
2020
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oai:doaj.org-article:d8fcbb763bac4e7e81b39c69ddf0ad9d2021-12-02T14:40:52ZIn vitro self-replication and multicistronic expression of large synthetic genomes10.1038/s41467-020-14694-22041-1723https://doaj.org/article/d8fcbb763bac4e7e81b39c69ddf0ad9d2020-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-14694-2https://doaj.org/toc/2041-1723A main objective of synthetic biology is the creation of chemical systems capable of replication and evolution. Here, the authors demonstrate combined self-replication and expression of multipartite genomes in vitro.K. LibicherR. HornbergerM. HeymannH. MutschlerNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-8 (2020) |
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Science Q K. Libicher R. Hornberger M. Heymann H. Mutschler In vitro self-replication and multicistronic expression of large synthetic genomes |
description |
A main objective of synthetic biology is the creation of chemical systems capable of replication and evolution. Here, the authors demonstrate combined self-replication and expression of multipartite genomes in vitro. |
format |
article |
author |
K. Libicher R. Hornberger M. Heymann H. Mutschler |
author_facet |
K. Libicher R. Hornberger M. Heymann H. Mutschler |
author_sort |
K. Libicher |
title |
In vitro self-replication and multicistronic expression of large synthetic genomes |
title_short |
In vitro self-replication and multicistronic expression of large synthetic genomes |
title_full |
In vitro self-replication and multicistronic expression of large synthetic genomes |
title_fullStr |
In vitro self-replication and multicistronic expression of large synthetic genomes |
title_full_unstemmed |
In vitro self-replication and multicistronic expression of large synthetic genomes |
title_sort |
in vitro self-replication and multicistronic expression of large synthetic genomes |
publisher |
Nature Portfolio |
publishDate |
2020 |
url |
https://doaj.org/article/d8fcbb763bac4e7e81b39c69ddf0ad9d |
work_keys_str_mv |
AT klibicher invitroselfreplicationandmulticistronicexpressionoflargesyntheticgenomes AT rhornberger invitroselfreplicationandmulticistronicexpressionoflargesyntheticgenomes AT mheymann invitroselfreplicationandmulticistronicexpressionoflargesyntheticgenomes AT hmutschler invitroselfreplicationandmulticistronicexpressionoflargesyntheticgenomes |
_version_ |
1718390139313455104 |