Weight outcome after 2 years of a diet that excludes six processed foods: exploratory study of the “1,2,3 diet” in a moderately obese population
Rodi Courie,1 Martin Gaillard,2,3 Panagiotis Lainas,2,3 Boris Hansel,1 Sylvie Naveau,1,3 Ibrahim Dagher,2,3 Hadrien Tranchart2,3 1Department of Hepato-Gastroenterology and Nutrition, Antoine Béclère Hospital (AP-HP), Clamart, France; 2Department of Digestive Minimally Invasive...
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Dove Medical Press
2018
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oai:doaj.org-article:d9087047b8e44d8cb6aab4cfb50931932021-12-02T09:04:52ZWeight outcome after 2 years of a diet that excludes six processed foods: exploratory study of the “1,2,3 diet” in a moderately obese population1178-7007https://doaj.org/article/d9087047b8e44d8cb6aab4cfb50931932018-07-01T00:00:00Zhttps://www.dovepress.com/weight-outcome-after-2-years-of-a-diet-that-excludes-six-processed-foo-peer-reviewed-article-DMSOhttps://doaj.org/toc/1178-7007Rodi Courie,1 Martin Gaillard,2,3 Panagiotis Lainas,2,3 Boris Hansel,1 Sylvie Naveau,1,3 Ibrahim Dagher,2,3 Hadrien Tranchart2,3 1Department of Hepato-Gastroenterology and Nutrition, Antoine Béclère Hospital (AP-HP), Clamart, France; 2Department of Digestive Minimally Invasive Surgery, Antoine Béclère Hospital (AP-HP), Clamart, France; 3Paris-Saclay University, INSERM U1193, Orsay, France Background: The Paleolithic diet, a diet devoid of food-processing procedure, seems to produce a greater decrease in weight compared to healthy reference diets but its limited food choices make it difficult to implement in our modern times where refined food is dominant.Objective: To evaluate the effects of a 2-year diet that excludes only six refined foodstuffs implicated in obesity. Professional contact was kept minimal to approximate the approach used by most dieters.Design: Single-arm, open-label, exploratory study.Setting: One academic medical center, outpatient setting.Patients: One hundred and five subjects with a mean age of 50 (SD, 14 years) and mean body mass index of 30.5 kg/m² (SD, 4 kg/m²). Thirty-nine percent had type 2 diabetes.Intervention: An ad libitum diet that excludes six refined foodstuffs (margarine, vegetable oils, butter, cream, processed meat, and sugary drinks) called the “1,2,3 diet”.Outcomes: Weight at 2 years was the primary outcome. Secondary outcomes included number of patients who lost more than 5% of initial body weight, glycated hemoglobin (HbA1c) level, and changes in dietary behavior.Results: Average weight loss was 4.8 kg (p<0.001), representing 5.6% of their initial body weight. Among completers (51%), the average weight loss was 5.5 kg (p<0.001), and 56% had a reduction of at least 5% of their initial body weight. Among diabetics, weight loss was similar to nondiabetics, and mean HbA1c level decreased by 1% (p=0.001) without modification in glucose-lowering medications. A higher intake of bread, dairy products, chocolate, and fresh fruits was the typical trend in dietary changes reported by completers.Conclusion: In this exploratory study, there was a significant long-term weight loss with the “1,2,3 diet” despite minimal professional contact. Given the lack of a control group and high attrition rate, further evaluation of this diet is warranted. Keywords: traditional diet, obesity, type 2 diabetes, refined food, satiety, leptin sensitivity Courie RGaillard MLainas PHansel BNaveau SDagher ITranchart HDove Medical Pressarticletraditional dietobesitytype 2 diabetesrefined foodsatietyleptin sensitivitySpecialties of internal medicineRC581-951ENDiabetes, Metabolic Syndrome and Obesity: Targets and Therapy, Vol Volume 11, Pp 345-355 (2018) |
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traditional diet obesity type 2 diabetes refined food satiety leptin sensitivity Specialties of internal medicine RC581-951 |
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traditional diet obesity type 2 diabetes refined food satiety leptin sensitivity Specialties of internal medicine RC581-951 Courie R Gaillard M Lainas P Hansel B Naveau S Dagher I Tranchart H Weight outcome after 2 years of a diet that excludes six processed foods: exploratory study of the “1,2,3 diet” in a moderately obese population |
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Rodi Courie,1 Martin Gaillard,2,3 Panagiotis Lainas,2,3 Boris Hansel,1 Sylvie Naveau,1,3 Ibrahim Dagher,2,3 Hadrien Tranchart2,3 1Department of Hepato-Gastroenterology and Nutrition, Antoine Béclère Hospital (AP-HP), Clamart, France; 2Department of Digestive Minimally Invasive Surgery, Antoine Béclère Hospital (AP-HP), Clamart, France; 3Paris-Saclay University, INSERM U1193, Orsay, France Background: The Paleolithic diet, a diet devoid of food-processing procedure, seems to produce a greater decrease in weight compared to healthy reference diets but its limited food choices make it difficult to implement in our modern times where refined food is dominant.Objective: To evaluate the effects of a 2-year diet that excludes only six refined foodstuffs implicated in obesity. Professional contact was kept minimal to approximate the approach used by most dieters.Design: Single-arm, open-label, exploratory study.Setting: One academic medical center, outpatient setting.Patients: One hundred and five subjects with a mean age of 50 (SD, 14 years) and mean body mass index of 30.5 kg/m² (SD, 4 kg/m²). Thirty-nine percent had type 2 diabetes.Intervention: An ad libitum diet that excludes six refined foodstuffs (margarine, vegetable oils, butter, cream, processed meat, and sugary drinks) called the “1,2,3 diet”.Outcomes: Weight at 2 years was the primary outcome. Secondary outcomes included number of patients who lost more than 5% of initial body weight, glycated hemoglobin (HbA1c) level, and changes in dietary behavior.Results: Average weight loss was 4.8 kg (p<0.001), representing 5.6% of their initial body weight. Among completers (51%), the average weight loss was 5.5 kg (p<0.001), and 56% had a reduction of at least 5% of their initial body weight. Among diabetics, weight loss was similar to nondiabetics, and mean HbA1c level decreased by 1% (p=0.001) without modification in glucose-lowering medications. A higher intake of bread, dairy products, chocolate, and fresh fruits was the typical trend in dietary changes reported by completers.Conclusion: In this exploratory study, there was a significant long-term weight loss with the “1,2,3 diet” despite minimal professional contact. Given the lack of a control group and high attrition rate, further evaluation of this diet is warranted. Keywords: traditional diet, obesity, type 2 diabetes, refined food, satiety, leptin sensitivity |
| format |
article |
| author |
Courie R Gaillard M Lainas P Hansel B Naveau S Dagher I Tranchart H |
| author_facet |
Courie R Gaillard M Lainas P Hansel B Naveau S Dagher I Tranchart H |
| author_sort |
Courie R |
| title |
Weight outcome after 2 years of a diet that excludes six processed foods: exploratory study of the “1,2,3 diet” in a moderately obese population |
| title_short |
Weight outcome after 2 years of a diet that excludes six processed foods: exploratory study of the “1,2,3 diet” in a moderately obese population |
| title_full |
Weight outcome after 2 years of a diet that excludes six processed foods: exploratory study of the “1,2,3 diet” in a moderately obese population |
| title_fullStr |
Weight outcome after 2 years of a diet that excludes six processed foods: exploratory study of the “1,2,3 diet” in a moderately obese population |
| title_full_unstemmed |
Weight outcome after 2 years of a diet that excludes six processed foods: exploratory study of the “1,2,3 diet” in a moderately obese population |
| title_sort |
weight outcome after 2 years of a diet that excludes six processed foods: exploratory study of the “1,2,3 diet” in a moderately obese population |
| publisher |
Dove Medical Press |
| publishDate |
2018 |
| url |
https://doaj.org/article/d9087047b8e44d8cb6aab4cfb5093193 |
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