Integrative and comparative genomic analyses identify clinically relevant pulmonary carcinoid groups and unveil the supra-carcinoids
The worldwide incidence of pulmonary carcinoids is increasing, but little is known about their molecular characteristics. Here, Alcala and colleagues present a multi-omics analysis of these tumours, revealing distinct molecular and prognostic subgroups.
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2019
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oai:doaj.org-article:d910423db1664141b7a3767146ac820a2021-12-02T16:50:57ZIntegrative and comparative genomic analyses identify clinically relevant pulmonary carcinoid groups and unveil the supra-carcinoids10.1038/s41467-019-11276-92041-1723https://doaj.org/article/d910423db1664141b7a3767146ac820a2019-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-11276-9https://doaj.org/toc/2041-1723The worldwide incidence of pulmonary carcinoids is increasing, but little is known about their molecular characteristics. Here, Alcala and colleagues present a multi-omics analysis of these tumours, revealing distinct molecular and prognostic subgroups.N. AlcalaN. LeblayA. A. G. GabrielL. MangianteD. HervasT. GiffonA. S. SertierA. FerrariJ. DerksA. GhantousT. M. DelhommeA. ChabrierC. CueninB. Abedi-ArdekaniA. BolandR. OlasoV. MeyerJ. AltmullerF. Le Calvez-KelmG. DurandC. VoegeleS. BoyaultL. MoonenN. LemaitreP. LorimierA. C. ToffartA. SoltermannJ. H. ClementJ. SaengerJ. K. FieldM. BrevetC. Blanc-FournierF. Galateau-SalleN. Le StangP. A. RussellG. WrightG. SozziU. PastorinoS. LacommeJ. M. VignaudV. HofmanP. HofmanO. T. BrustugunM. Lund-IversenV. Thomas de MontprevilleL. A. MuscarellaP. GrazianoH. PopperJ. StojsicJ. F. DeleuzeZ. HercegA. ViariP. NuernbergG. PelosiA. M. C. DingemansM. MilioneL. RozL. BrcicM. VolanteM. G. PapottiC. CauxJ. SandovalH. Hernandez-VargasE. BrambillaE. J. M. SpeelN. GirardS. LantuejoulJ. D. McKayM. FollL. Fernandez-CuestaNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-21 (2019) |
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Science Q N. Alcala N. Leblay A. A. G. Gabriel L. Mangiante D. Hervas T. Giffon A. S. Sertier A. Ferrari J. Derks A. Ghantous T. M. Delhomme A. Chabrier C. Cuenin B. Abedi-Ardekani A. Boland R. Olaso V. Meyer J. Altmuller F. Le Calvez-Kelm G. Durand C. Voegele S. Boyault L. Moonen N. Lemaitre P. Lorimier A. C. Toffart A. Soltermann J. H. Clement J. Saenger J. K. Field M. Brevet C. Blanc-Fournier F. Galateau-Salle N. Le Stang P. A. Russell G. Wright G. Sozzi U. Pastorino S. Lacomme J. M. Vignaud V. Hofman P. Hofman O. T. Brustugun M. Lund-Iversen V. Thomas de Montpreville L. A. Muscarella P. Graziano H. Popper J. Stojsic J. F. Deleuze Z. Herceg A. Viari P. Nuernberg G. Pelosi A. M. C. Dingemans M. Milione L. Roz L. Brcic M. Volante M. G. Papotti C. Caux J. Sandoval H. Hernandez-Vargas E. Brambilla E. J. M. Speel N. Girard S. Lantuejoul J. D. McKay M. Foll L. Fernandez-Cuesta Integrative and comparative genomic analyses identify clinically relevant pulmonary carcinoid groups and unveil the supra-carcinoids |
description |
The worldwide incidence of pulmonary carcinoids is increasing, but little is known about their molecular characteristics. Here, Alcala and colleagues present a multi-omics analysis of these tumours, revealing distinct molecular and prognostic subgroups. |
format |
article |
author |
N. Alcala N. Leblay A. A. G. Gabriel L. Mangiante D. Hervas T. Giffon A. S. Sertier A. Ferrari J. Derks A. Ghantous T. M. Delhomme A. Chabrier C. Cuenin B. Abedi-Ardekani A. Boland R. Olaso V. Meyer J. Altmuller F. Le Calvez-Kelm G. Durand C. Voegele S. Boyault L. Moonen N. Lemaitre P. Lorimier A. C. Toffart A. Soltermann J. H. Clement J. Saenger J. K. Field M. Brevet C. Blanc-Fournier F. Galateau-Salle N. Le Stang P. A. Russell G. Wright G. Sozzi U. Pastorino S. Lacomme J. M. Vignaud V. Hofman P. Hofman O. T. Brustugun M. Lund-Iversen V. Thomas de Montpreville L. A. Muscarella P. Graziano H. Popper J. Stojsic J. F. Deleuze Z. Herceg A. Viari P. Nuernberg G. Pelosi A. M. C. Dingemans M. Milione L. Roz L. Brcic M. Volante M. G. Papotti C. Caux J. Sandoval H. Hernandez-Vargas E. Brambilla E. J. M. Speel N. Girard S. Lantuejoul J. D. McKay M. Foll L. Fernandez-Cuesta |
author_facet |
N. Alcala N. Leblay A. A. G. Gabriel L. Mangiante D. Hervas T. Giffon A. S. Sertier A. Ferrari J. Derks A. Ghantous T. M. Delhomme A. Chabrier C. Cuenin B. Abedi-Ardekani A. Boland R. Olaso V. Meyer J. Altmuller F. Le Calvez-Kelm G. Durand C. Voegele S. Boyault L. Moonen N. Lemaitre P. Lorimier A. C. Toffart A. Soltermann J. H. Clement J. Saenger J. K. Field M. Brevet C. Blanc-Fournier F. Galateau-Salle N. Le Stang P. A. Russell G. Wright G. Sozzi U. Pastorino S. Lacomme J. M. Vignaud V. Hofman P. Hofman O. T. Brustugun M. Lund-Iversen V. Thomas de Montpreville L. A. Muscarella P. Graziano H. Popper J. Stojsic J. F. Deleuze Z. Herceg A. Viari P. Nuernberg G. Pelosi A. M. C. Dingemans M. Milione L. Roz L. Brcic M. Volante M. G. Papotti C. Caux J. Sandoval H. Hernandez-Vargas E. Brambilla E. J. M. Speel N. Girard S. Lantuejoul J. D. McKay M. Foll L. Fernandez-Cuesta |
author_sort |
N. Alcala |
title |
Integrative and comparative genomic analyses identify clinically relevant pulmonary carcinoid groups and unveil the supra-carcinoids |
title_short |
Integrative and comparative genomic analyses identify clinically relevant pulmonary carcinoid groups and unveil the supra-carcinoids |
title_full |
Integrative and comparative genomic analyses identify clinically relevant pulmonary carcinoid groups and unveil the supra-carcinoids |
title_fullStr |
Integrative and comparative genomic analyses identify clinically relevant pulmonary carcinoid groups and unveil the supra-carcinoids |
title_full_unstemmed |
Integrative and comparative genomic analyses identify clinically relevant pulmonary carcinoid groups and unveil the supra-carcinoids |
title_sort |
integrative and comparative genomic analyses identify clinically relevant pulmonary carcinoid groups and unveil the supra-carcinoids |
publisher |
Nature Portfolio |
publishDate |
2019 |
url |
https://doaj.org/article/d910423db1664141b7a3767146ac820a |
work_keys_str_mv |
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