Binding free energy decomposition and multiple unbinding paths of buried ligands in a PreQ1 riboswitch.
Riboswitches are naturally occurring RNA elements that control bacterial gene expression by binding to specific small molecules. They serve as important models for RNA-small molecule recognition and have also become a novel class of targets for developing antibiotics. Here, we carried out convention...
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Autores principales: | Guodong Hu, Huan-Xiang Zhou |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/d91d631acf674b03bf4c04f4c7c37a31 |
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