Molecular analysis of Aedes aegypti classical protein tyrosine phosphatases uncovers an ortholog of mammalian PTP-1B implicated in the control of egg production in mosquitoes.

Molecular analysis of Aedes aegypti classical protein tyrosine phosphatases uncovers an ortholog of mammalian PTP-1B implicated in the control of egg production in mosquitoes.

<h4>Background</h4>Protein Tyrosine Phosphatases (PTPs) are enzymes that catalyze phosphotyrosine dephosphorylation and modulate cell differentiation, growth and metabolism. In mammals, PTPs play a key role in the modulation of canonical pathways involved in metabolism and immunity. PTP1...

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Autores principales: Debora Monteiro Moretti, Lalima Gagan Ahuja, Rodrigo Dutra Nunes, Cecília Oliveira Cudischevitch, Carlos Renato Oliveira Daumas-Filho, Priscilla Medeiros-Castro, Guilherme Ventura-Martins, Willy Jablonka, Felipe Gazos-Lopes, Raquel Senna, Marcos Henrique Ferreira Sorgine, Klaus Hartfelder, Margareth Capurro, Georgia Correa Atella, Rafael Dias Mesquita, Mário Alberto Cardoso Silva-Neto
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2014
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/d92719297a4745678ca6057dfdccd377
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