Functional implications of novel human acid sphingomyelinase splice variants.

<h4>Background</h4>Acid sphingomyelinase (ASM) hydrolyses sphingomyelin and generates the lipid messenger ceramide, which mediates a variety of stress-related cellular processes. The pathological effects of dysregulated ASM activity are evident in several human diseases and indicate an i...

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Autores principales: Cosima Rhein, Philipp Tripal, Angela Seebahn, Alice Konrad, Marcel Kramer, Christine Nagel, Jonas Kemper, Jens Bode, Christiane Mühle, Erich Gulbins, Martin Reichel, Cord-Michael Becker, Johannes Kornhuber
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
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Acceso en línea:https://doaj.org/article/d93747c8225746268ebeac7480e22c92
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