IGF2 promotes growth of adrenocortical carcinoma cells, but its overexpression does not modify phenotypic and molecular features of adrenocortical carcinoma.

Insulin-like growth factor 2 (IGF2) overexpression is an important molecular marker of adrenocortical carcinoma (ACC), which is a rare but devastating endocrine cancer. It is not clear whether IGF2 overexpression modifies the biology and growth of this cancer, thus more studies are required before I...

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Auteurs principaux: Marine Guillaud-Bataille, Bruno Ragazzon, Aurélien de Reyniès, Claire Chevalier, Isabelle Francillard, Olivia Barreau, Virginie Steunou, Johann Guillemot, Frédérique Tissier, Marthe Rizk-Rabin, Fernande René-Corail, Abir Al Ghuzlan, Guillaume Assié, Xavier Bertagna, Eric Baudin, Yves Le Bouc, Jérôme Bertherat, Eric Clauser
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2014
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Accès en ligne:https://doaj.org/article/d93b7d6056db476b9f50e1676676fe75
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