Multi-product biorefinery from Arthrospira platensis biomass as feedstock for bioethanol and lactic acid production

Abstract With the aim to reach the maximum recovery of bulk and specialty bioproducts while minimizing waste generation, a multi-product biorefinery for ethanol and lactic acid production from the biomass of cyanobacterium Arthrospira platensis was investigated. Therefore, the residual biomass resul...

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Autores principales:	Diego A. Esquivel-Hernández, Anna Pennacchio, Mario A. Torres-Acosta, Roberto Parra-Saldívar, Luciana Porto de Souza Vandenberghe, Vincenza Faraco
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/d93cc001d0e047bf80e9810530850ed3
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spelling	oai:doaj.org-article:d93cc001d0e047bf80e9810530850ed32021-12-02T18:51:14ZMulti-product biorefinery from Arthrospira platensis biomass as feedstock for bioethanol and lactic acid production10.1038/s41598-021-97803-52045-2322https://doaj.org/article/d93cc001d0e047bf80e9810530850ed32021-09-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-97803-5https://doaj.org/toc/2045-2322Abstract With the aim to reach the maximum recovery of bulk and specialty bioproducts while minimizing waste generation, a multi-product biorefinery for ethanol and lactic acid production from the biomass of cyanobacterium Arthrospira platensis was investigated. Therefore, the residual biomass resulting from different pretreatments consisting of supercritical fluid extraction (SF) and microwave assisted extraction with non-polar (MN) and polar solvents (MP), previously applied on A. platensis to extract bioactive metabolites, was further valorized. In particular, it was used as a substrate for fermentation with Saccharomyces cerevisiae LPB-287 and Lactobacillus acidophilus ATCC 43121 to produce bioethanol (BE) and lactic acid (LA), respectively. The maximum concentrations achieved were 3.02 ± 0.07 g/L of BE by the MN process at 120 rpm 30 °C, and 9.67 ± 0.05 g/L of LA by the SF process at 120 rpm 37 °C. An economic analysis of BE and LA production was carried out to elucidate the impact of fermentation scale, fermenter costs, production titer, fermentation time and cyanobacterial biomass production cost. The results indicated that the critical variables are fermenter scale, equipment cost, and product titer; time process was analyzed but was not critical. As scale increased, costs tended to stabilize, but also more product was generated, which causes production costs per unit of product to sharply decrease. The median value of production cost was US$ 1.27 and US$ 0.39, for BE and LA, respectively, supporting the concept of cyanobacterium biomass being used for fermentation and subsequent extraction to obtain ethanol and lactic acid as end products from A. platensis.Diego A. Esquivel-HernándezAnna PennacchioMario A. Torres-AcostaRoberto Parra-SaldívarLuciana Porto de Souza VandenbergheVincenza FaracoNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Diego A. Esquivel-Hernández Anna Pennacchio Mario A. Torres-Acosta Roberto Parra-Saldívar Luciana Porto de Souza Vandenberghe Vincenza Faraco Multi-product biorefinery from Arthrospira platensis biomass as feedstock for bioethanol and lactic acid production
description	Abstract With the aim to reach the maximum recovery of bulk and specialty bioproducts while minimizing waste generation, a multi-product biorefinery for ethanol and lactic acid production from the biomass of cyanobacterium Arthrospira platensis was investigated. Therefore, the residual biomass resulting from different pretreatments consisting of supercritical fluid extraction (SF) and microwave assisted extraction with non-polar (MN) and polar solvents (MP), previously applied on A. platensis to extract bioactive metabolites, was further valorized. In particular, it was used as a substrate for fermentation with Saccharomyces cerevisiae LPB-287 and Lactobacillus acidophilus ATCC 43121 to produce bioethanol (BE) and lactic acid (LA), respectively. The maximum concentrations achieved were 3.02 ± 0.07 g/L of BE by the MN process at 120 rpm 30 °C, and 9.67 ± 0.05 g/L of LA by the SF process at 120 rpm 37 °C. An economic analysis of BE and LA production was carried out to elucidate the impact of fermentation scale, fermenter costs, production titer, fermentation time and cyanobacterial biomass production cost. The results indicated that the critical variables are fermenter scale, equipment cost, and product titer; time process was analyzed but was not critical. As scale increased, costs tended to stabilize, but also more product was generated, which causes production costs per unit of product to sharply decrease. The median value of production cost was US$ 1.27 and US$ 0.39, for BE and LA, respectively, supporting the concept of cyanobacterium biomass being used for fermentation and subsequent extraction to obtain ethanol and lactic acid as end products from A. platensis.
format	article
author	Diego A. Esquivel-Hernández Anna Pennacchio Mario A. Torres-Acosta Roberto Parra-Saldívar Luciana Porto de Souza Vandenberghe Vincenza Faraco
author_facet	Diego A. Esquivel-Hernández Anna Pennacchio Mario A. Torres-Acosta Roberto Parra-Saldívar Luciana Porto de Souza Vandenberghe Vincenza Faraco
author_sort	Diego A. Esquivel-Hernández
title	Multi-product biorefinery from Arthrospira platensis biomass as feedstock for bioethanol and lactic acid production
title_short	Multi-product biorefinery from Arthrospira platensis biomass as feedstock for bioethanol and lactic acid production
title_full	Multi-product biorefinery from Arthrospira platensis biomass as feedstock for bioethanol and lactic acid production
title_fullStr	Multi-product biorefinery from Arthrospira platensis biomass as feedstock for bioethanol and lactic acid production
title_full_unstemmed	Multi-product biorefinery from Arthrospira platensis biomass as feedstock for bioethanol and lactic acid production
title_sort	multi-product biorefinery from arthrospira platensis biomass as feedstock for bioethanol and lactic acid production
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/d93cc001d0e047bf80e9810530850ed3
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Multi-product biorefinery from Arthrospira platensis biomass as feedstock for bioethanol and lactic acid production

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