An R package for generic modular response analysis and its application to estrogen and retinoic acid receptor crosstalk

An R package for generic modular response analysis and its application to estrogen and retinoic acid receptor crosstalk

Abstract Modular response analysis (MRA) is a widely used inference technique developed to uncover directions and strengths of connections in molecular networks under a steady-state condition by means of perturbation experiments. We devised several extensions of this methodology to search genomic da...

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Autores principales: Gabriel Jimenez-Dominguez, Patrice Ravel, Stéphan Jalaguier, Vincent Cavaillès, Jacques Colinge
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/d94098b1f0d3446eb30d3bf3eb359a2a
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