Discovery of multiple anti-CRISPRs highlights anti-defense gene clustering in mobile genetic elements
Mobile genetic elements have evolved anti-CRISPR (Acr) proteins to bypass the immunity provided by prokaryotic CRISPR–Cas systems. Here, the authors identify 11 type I Acrs encoded on mobile genetic elements, and show that acr loci neighborhoods can be used to discover inhibitors of other bacterial...
Saved in:
Main Authors: | Rafael Pinilla-Redondo, Saadlee Shehreen, Nicole D. Marino, Robert D. Fagerlund, Chris M. Brown, Søren J. Sørensen, Peter C. Fineran, Joseph Bondy-Denomy |
---|---|
Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2020
|
Subjects: | |
Online Access: | https://doaj.org/article/d9475332a4d84a3d8ba6e1f2654da4ac |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
The solution structure of an anti-CRISPR protein
by: Karen L. Maxwell, et al.
Published: (2016) -
Machine-learning approach expands the repertoire of anti-CRISPR protein families
by: Ayal B. Gussow, et al.
Published: (2020) -
A New Group of Phage Anti-CRISPR Genes Inhibits the Type I-E CRISPR-Cas System of <named-content content-type="genus-species">Pseudomonas aeruginosa</named-content>
by: April Pawluk, et al.
Published: (2014) -
Anti-CRISPR-mediated control of gene editing and synthetic circuits in eukaryotic cells
by: Muneaki Nakamura, et al.
Published: (2019) -
The small, slow and specialized CRISPR and anti-CRISPR of Escherichia and Salmonella.
by: Marie Touchon, et al.
Published: (2010)