Single-cell profiling of tumor heterogeneity and the microenvironment in advanced non-small cell lung cancer

Comprehensive profiles of tumour and microenvironment are critical to understand heterogeneity in non-small cell lung cancer (NSCLC). Here, the authors profile 42 late-stage NSCLC patients with single-cell RNA-seq, revealing immune landscapes that are associated with cancer subtype or heterogeneity.

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Autores principales:	Fengying Wu, Jue Fan, Yayi He, Anwen Xiong, Jia Yu, Yixin Li, Yan Zhang, Wencheng Zhao, Fei Zhou, Wei Li, Jie Zhang, Xiaosheng Zhang, Meng Qiao, Guanghui Gao, Shanhao Chen, Xiaoxia Chen, Xuefei Li, Likun Hou, Chunyan Wu, Chunxia Su, Shengxiang Ren, Margarete Odenthal, Reinhard Buettner, Nan Fang, Caicun Zhou
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/d949270af6d44c9389feb2e044361388
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spelling	oai:doaj.org-article:d949270af6d44c9389feb2e0443613882021-12-02T14:29:01ZSingle-cell profiling of tumor heterogeneity and the microenvironment in advanced non-small cell lung cancer10.1038/s41467-021-22801-02041-1723https://doaj.org/article/d949270af6d44c9389feb2e0443613882021-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-22801-0https://doaj.org/toc/2041-1723Comprehensive profiles of tumour and microenvironment are critical to understand heterogeneity in non-small cell lung cancer (NSCLC). Here, the authors profile 42 late-stage NSCLC patients with single-cell RNA-seq, revealing immune landscapes that are associated with cancer subtype or heterogeneity.Fengying WuJue FanYayi HeAnwen XiongJia YuYixin LiYan ZhangWencheng ZhaoFei ZhouWei LiJie ZhangXiaosheng ZhangMeng QiaoGuanghui GaoShanhao ChenXiaoxia ChenXuefei LiLikun HouChunyan WuChunxia SuShengxiang RenMargarete OdenthalReinhard BuettnerNan FangCaicun ZhouNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Fengying Wu Jue Fan Yayi He Anwen Xiong Jia Yu Yixin Li Yan Zhang Wencheng Zhao Fei Zhou Wei Li Jie Zhang Xiaosheng Zhang Meng Qiao Guanghui Gao Shanhao Chen Xiaoxia Chen Xuefei Li Likun Hou Chunyan Wu Chunxia Su Shengxiang Ren Margarete Odenthal Reinhard Buettner Nan Fang Caicun Zhou Single-cell profiling of tumor heterogeneity and the microenvironment in advanced non-small cell lung cancer
description	Comprehensive profiles of tumour and microenvironment are critical to understand heterogeneity in non-small cell lung cancer (NSCLC). Here, the authors profile 42 late-stage NSCLC patients with single-cell RNA-seq, revealing immune landscapes that are associated with cancer subtype or heterogeneity.
format	article
author	Fengying Wu Jue Fan Yayi He Anwen Xiong Jia Yu Yixin Li Yan Zhang Wencheng Zhao Fei Zhou Wei Li Jie Zhang Xiaosheng Zhang Meng Qiao Guanghui Gao Shanhao Chen Xiaoxia Chen Xuefei Li Likun Hou Chunyan Wu Chunxia Su Shengxiang Ren Margarete Odenthal Reinhard Buettner Nan Fang Caicun Zhou
author_facet	Fengying Wu Jue Fan Yayi He Anwen Xiong Jia Yu Yixin Li Yan Zhang Wencheng Zhao Fei Zhou Wei Li Jie Zhang Xiaosheng Zhang Meng Qiao Guanghui Gao Shanhao Chen Xiaoxia Chen Xuefei Li Likun Hou Chunyan Wu Chunxia Su Shengxiang Ren Margarete Odenthal Reinhard Buettner Nan Fang Caicun Zhou
author_sort	Fengying Wu
title	Single-cell profiling of tumor heterogeneity and the microenvironment in advanced non-small cell lung cancer
title_short	Single-cell profiling of tumor heterogeneity and the microenvironment in advanced non-small cell lung cancer
title_full	Single-cell profiling of tumor heterogeneity and the microenvironment in advanced non-small cell lung cancer
title_fullStr	Single-cell profiling of tumor heterogeneity and the microenvironment in advanced non-small cell lung cancer
title_full_unstemmed	Single-cell profiling of tumor heterogeneity and the microenvironment in advanced non-small cell lung cancer
title_sort	single-cell profiling of tumor heterogeneity and the microenvironment in advanced non-small cell lung cancer
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/d949270af6d44c9389feb2e044361388
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Single-cell profiling of tumor heterogeneity and the microenvironment in advanced non-small cell lung cancer

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